Effects of Nattokinase on Inflammation and Cardiovascular Risk Markers in Patients With Dyslipidemia

Inclusion Criteria:

• Both sexes;

• Over 18 years of age;

• Isolated increase in LDL-c (LDL-c ≥ 160 mg/dL);

• Isolated increase in triglycerides (TG ≥ 150 mg/dL or ≥ 175 mg/dL, without fasting);

• increased LDL-c (LDL-c ≥ 160 mg/dL)

• TG (TG ≥ 150 mg/dL or ≥ 175 mg/dL, without fasting);

• Reduction in HDL-c (men < 40 mg/dL and women < 50 mg/dL) alone or in associationwith an increase in LDL-c or TG. If TG ≥ 400 mg/dL.

• Individuals who are already using lipid-lowering therapy (statins or non-statins)will also be included.

Exclusion Criteria:

• Participants with autoimmune and infectious diseases, diabetes, cancer and AIDS;

• Pregnant women;

• Participants using catabolic drugs or antibiotics

• Participants on anticoagulant medication

• Participants using antioxidant vitamin supplements, prebiotic, probiotic orsynbiotic and who are allergic to corn or soy starch.