Strategy for Prompt and Effective Thoracentesis in the Emergency Department

Last updated: December 4, 2024
Sponsor: University of Aarhus
Overall Status: Active - Recruiting

Phase

N/A

Condition

Heart Failure

Chest Pain

Congestive Heart Failure

Treatment

Gravity fluid drainage in the radiology department

Manual drainage in the emergency department

Clinical Study ID

NCT06180603
AU307272
  • Ages > 18
  • All Genders

Study Summary

The SPEEDTAP-trial is a prospective, randomised, investigator-initiated, multicenter, clinical superior trial investigating two thoracentesis methods in four emergency departments (ED) in Central Denmark Region. Patients are randomised to either manual fluid removal in the ED or passively fluid drainage using gravity in the radiology department (standard of care). Primary outcome: time from clinical indication to complete drainage and 188 patients will be included. Key secondary outcomes include length of stay, ED admission to ED discharge and safety end-points.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients ≥ 18 years admitted to the ED

  • Pleural effusion detected by any imaging modality (e.g., bedside ultrasound, chestx-ray, computed tomography)

  • Clinically justified need for thoracentesis ( symptomatic relief and/or define theetiology of the effusion

  • Without contraindication for thoracentesis in the emergency department (e.g.,anticoagulant treatment)

Exclusion

Exclusion Criteria:

  • Life-threatening respiratory distress

  • Not able to give consent

  • Previous pleurodesis

  • Effusion does not appear free-flowing due to septations or loculations / suspectedempyema

  • Prior enrollment in the trial

  • If randomization is not possible because decision to insert a pigtail catheter ismade in the radiology department

Study Design

Total Participants: 188
Treatment Group(s): 2
Primary Treatment: Gravity fluid drainage in the radiology department
Phase:
Study Start date:
January 15, 2024
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • Aarhus University Hospital

    Aarhus, Central Denmark Region 8200
    Denmark

    Site Not Available

  • Gødstrup Regional Hospital

    Gødstrup, Central Denmark Region 7400
    Denmark

    Site Not Available

  • Horsens Regional Hospital

    Horsens, Central Denmark Region 8700
    Denmark

    Active - Recruiting

  • Randers Regional Hospital

    Randers, Central Denmark Region 8930
    Denmark

    Active - Recruiting

  • Aalborg University Hospital

    Aalborg, North Denmark Region
    Denmark

    Active - Recruiting

  • Esbjerg sygehus

    Esbjerg, South Region Denmark
    Denmark

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.