Laser Treatment of Reticular Leg Veins Vs. Sclerotherapy

Last updated: February 3, 2025
Sponsor: Derzhavin Tambov State University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Laser with Sclerotherapy

Laser ablation

Sclerotherapy

Clinical Study ID

NCT06175754
DerzhavinTambovSU
  • Ages 18-75
  • Female

Study Summary

Treatment of reticular veins with a 1064 nm long-pulsed Nd:YAG laser and combination of a 1064 nm Nd:YAG long pulse laser and sclerotherapy should be no less effective than sclerotherapy alone, and have a frequency of adverse events less then sclerotherapy alone.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • women over 18

  • reticular veins

  • signed informed consent to participate in the study

Exclusion

Exclusion Criteria:

  • diabetes mellitus

  • pregnancy or lactation

  • malignant neoplasms

  • inability or unwillingness of the patient to wear compression stockings

  • hypersensitivity to the polidocanol, cold, sunlight

  • concomitant diseases: bronchial asthma, severe liver and kidney disease, acutethrombosis and thrombophlebitis, infection of the skin and/or soft tissues,infectious diseases, arteriosclerosis, diabetic angiopathy, heart defects requiringsurgery, fever, toxic hyperthyroidism, obesity, tuberculosis, sepsis, violation ofthe cellular composition of the blood, all diseases requiring bed rest, heartdisease with decompensation phenomena,

  • known hereditary thrombophilia.

  • period after treatment of alcoholism

  • reception of oral contraceptives

  • sedentary lifestyle

Study Design

Total Participants: 174
Treatment Group(s): 3
Primary Treatment: Laser with Sclerotherapy
Phase:
Study Start date:
October 09, 2023
Estimated Completion Date:
December 09, 2025

Study Description

Reticular leg veins are mostly an aesthetic problem. Sclerotherapy is considered the gold standard for treatment them. However, this method has a high frequency of long persistent hyperpigmentation which decreases the patients' satisfaction. It is a reason to find another method of treatment. Another possible technique to treat reticular veins is the Nd:YAG long pulse 1064 nm transdermal laser or Nd:YAG laser combined with injection sclerotherapy. There are a few studies comparing sclerotherapy with laser treatment and combined treatment with sclerotherapy. But there are no prospective, randomized, comparative clinical trials of all three methods: the 1064 nm Nd:YAG long pulse laser, combined treatment of a 1064 nm Nd:YAG long pulse laser with sclerotherapy and sclerotherapy alone. The aim of current study is the efficacy assessment of the 1064 nm long-pulsed Nd:YAG laser, combined treatment of the 1064 nm Nd:YAG long pulse laser with sclerotherapy and sclerotherapy alone for the treatment of reticular leg veins and analysis of side effects to establish advantages and disadvantage of these methods and find the best option for treatment of reticular leg veins.

Connect with a study center

  • Bukina Oksana Vasilyevna

    Tambov, 392002
    Russian Federation

    Active - Recruiting

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