A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Last updated: August 6, 2025
Sponsor: Massachusetts General Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cancer

Treatment

Young Adults Coping with Cancer Together Intervention

Clinical Study ID

NCT06172907
23-472
  • Ages 25-39
  • All Genders

Study Summary

The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Either: (1) Currently receiving active cancer treatment (n=5) or are within twoyears of completing active treatment (n=5) at Massachusetts General Cancer Center (MGHCC), located in Boston, Massachusetts, United States, OR (2) are the partner ofan individual between the ages of 25-39 who is currently receiving treatment atMGHCC (n=5) or who has completed cancer treatment at MGHCC within the past two years (n=5)

  • Either: (1) Indicates a score ≥4 on the National Comprehensive Cancer Network (NCCN)adapted distress thermometer study screening questions, OR (2) are the partner of aparticipant indicating a score ≥4 on the NCCN adapted distress thermometer studyscreening questions

  • English-speaking

Exclusion

Exclusion Criteria:

• Uncontrolled psychosis, active suicidal ideation, or cognitive impairment

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: Young Adults Coping with Cancer Together Intervention
Phase:
Study Start date:
April 19, 2024
Estimated Completion Date:
June 30, 2026

Study Description

Young adults (YA) with cancer have unique challenges in coping, and their primary partners may experience burden and low self-efficacy related to caregiving. In this single-arm pilot trial, the investigators shall deliver an eight-session intervention to YAs with cancer and their self-identified partners who provide caregiving. The intervention is founded on principles from cognitive-behavioral therapy and couples-focused interventions, tailored for YA. The aim of the study is to assess the feasibility and acceptability of the intervention, which will inform refinements prior to a larger-scale clinical trial. This study will include 10 YAs and their partner-caregivers (N=20). Participants will complete surveys at baseline and after the intervention, and will be invited to complete optional semi-structured exit interviews.

Connect with a study center

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts 02114
    United States

    Active - Recruiting

  • Emerson Hospital/MGH Cancer Center

    Concord, Massachusetts 01742
    United States

    Active - Recruiting

  • Mass General at North Shore Cancer Center

    Danvers, Massachusetts 01923
    United States

    Active - Recruiting

  • Mass General at Newton Wellesley Hospital

    Newton, Massachusetts 02462
    United States

    Active - Recruiting

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