Hong Kong Cohort of Abnormal Sleep in Ageing Population (HK-ASAP): Focusing on Brain Health and Sleep Quality

Last updated: January 11, 2025
Sponsor: Chinese University of Hong Kong
Overall Status: Completed

Phase

N/A

Condition

Memory Problems

Sleep Disorders

Insomnia

Treatment

N/A

Clinical Study ID

NCT06170073
2023.496
  • Ages 55-95
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Poor sleep quality can significantly jeopardize the brain health, cognitive functions, daily activities, quality of life, and even be implicated as a key potential contributing factor in the development of accelerated cognitive decline and prodromal dementia. Consequently, research efforts to understand, and therefore potentially model, the effects of sleep quality on cognition and brain health are of great pragmatic values.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Chinese old adults are the ones who are over 60 years of chronological age.

  • Sleep disturbance: individual's subjective sleep quality is assessed using thePittsburgh Sleep Quality Index (PSQI) with a total score >5.

Exclusion

Exclusion Criteria:

  • History of bipolar disorders or psychosis.

  • History of major neurological deficits, including stroke, transient ischemic attackor brain tumor.

  • Unable to participant magnetic resonance imaging (MRI) scanning.

Study Design

Total Participants: 238
Study Start date:
October 01, 2023
Estimated Completion Date:
January 10, 2025

Study Description

Objectives: This study aims to investigate the cognitive changes in older adults with sleep disturbances, examine the neuroimaging contributors to poor sleep quality and cognitive deficits.

Connect with a study center

  • The Chinese University of Hong Kong

    Hong Kong, Tai Po 100000
    Hong Kong

    Site Not Available

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