A Study to Assess Collagenase Clostridium Histolyticum (CCH) in the Treatment of Plantar Fasciitis (PFA)

Key Inclusion Criteria:

• Have no significant medical history or examination findings related to the foot tobe treated, which in the investigator's opinion, would make the participantunsuitable for study intervention administration.

• Have a diagnosis of plantar fasciitis for ≥6 months, which has not responded toconservative therapies. Conservative therapies may include rest, physical therapy,splinting/bracing, orthotics, icing, physiotherapy, acetaminophen, corticosteroids,or nonsteroidal anti-inflammatory drugs (NSAIDs).

• Have current foot pain due to plantar fasciitis.

Key Exclusion Criteria:

• Has any musculoskeletal, neuromuscular, neurosensory, other neurological or relateddisorder that affects the participant's use of his/her feet and/or would impairhis/her completion of study assessments as determined by the investigator either dueto the disorder or due to pain.

• Has a clinically meaningful laboratory abnormality.

• Has a body mass index ≥35 kilograms per meter squared (kg/m^2).

• Has a known bleeding disorder, which, in the investigator's opinion, would make theparticipant unsuitable for enrollment in the study.