Effect of SNB on the QoR in Patients Undergoing Supratentorial Tumor Resection

Inclusion Criteria:

• age between 18 and 65;

• the diagnosis was supratentorial tumor;

• scheduled for elective supratentorial craniotomy with general anesthesia ;

• the American Society of Anesthesiologists physical status I-III;

Exclusion Criteria:

• the BMI≦18kg/m2 or BMI≧30kg/m2;

• refusing to sign written informed consent;

• anticipated surgery duration is too short (<2 h) or too long (>6 h);

• liver or kidney dysfunction, severe cardiopulmonary failure or nervous systemdisease ;

• with other malignancies ;

• severe hematological disease and / or abnormal coagulation function;

• fever, systemic and / or scalp infection;

• tumors are metastases, aneurysms, hemangioma, or located in the skull base, orlocated in functional brain areas such as language and movement;

• allergy to any drug used in this study;

• a history of craniotomy tumor resection;

• preoperative usage of antiinflammatory agents or analgesics;

• pregnant women, lactating women, illiterate people, people with cognitiveimpairment, a history of mental illness, unable to communicate and complete thescale assessment;

• patients with severe hemodynamic disturbances or other life-threateningcomplications during the operation, or those transferred to the intensive care unit (ICU) after surgery.