Action Observation and Motor Imagery Therapy in Parkinson's Disease

Last updated: December 14, 2023
Sponsor: Karamanoğlu Mehmetbey University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Parkinson's Disease

Dyskinesias

Treatment

Sham action observation and motor imagery therapy for rehabilitation

Action observation and motor imagery therapy for rehabilitation

Clinical Study ID

NCT06154356
E-11095095-050.01.04-154055
  • Ages 18-65
  • All Genders

Study Summary

In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in Parkinson's disease (PD). Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind.

The aim of this clinical trial is to test whether the application of AO and MI treatment in PD in addition to conventional rehabilitation programs has an additional effect on Balance, Functional Status and Quality of Life.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with a diagnosis of Parkinson's Disease
  • Hoehn and Yahr Stage 1-3

Exclusion

Exclusion Criteria:

  • Patients with cognitive dysfunction (those who cannot follow simple verbalinstructions)
  • Patients with severe hearing problems
  • Patients with severe vision problems
  • Patients with additional musculoskeletal system pathology that will affect physicalperformance (such as amputation, severe joint mobility limitation, peripheral nervedamage)
  • Patients with uncontrolled hypertension and diabetes mellitus
  • Patients with a history of symptomatic lung disease (such as asthma, chronicobstructive pulmonary disease, emphysema)
  • Patients with a history of symptomatic cardiac disease (such as coronary arterydisease, arrhythmia, heart failure)

Study Design

Total Participants: 54
Treatment Group(s): 2
Primary Treatment: Sham action observation and motor imagery therapy for rehabilitation
Phase:
Study Start date:
December 14, 2023
Estimated Completion Date:
December 30, 2024

Study Description

Parkinson's disease (PD) is a neurodegenerative disease with a chronic and progressive course. Freezing phenomena, gait disorders, and balance problems are common in PD. Gait and balance disorders and motor freezing attacks that occur as a result of PD increase the risk of falling, leading to a decrease in functional independence and quality of life. The main goal of Parkinson's rehabilitation is to ensure the maximum functional status and independence in daily living activities and to increase their quality of life.

In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in PD. Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind.

The aim of this clinical trial is to test whether the application of AO and MI treatment in PD in addition to conventional rehabilitation programs has an additional effect on Balance, Functional Status and Quality of Life.

Connect with a study center

  • Karaman Training and Research Hospital

    Karaman, 70200
    Turkey

    Active - Recruiting

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