Great Occipital Nerve Block Using Different Approach

Last updated: November 28, 2023
Sponsor: Keimyung University Dongsan Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pain

Chronic Pain

Treatment

GON block

Greater occipital nerve block

Clinical Study ID

NCT06149299
2023-10-025
  • Ages 20-80
  • All Genders

Study Summary

Great occipital nerve (GON) block is commonly applied for the pain management of occipital neuralgia, migraine, and cervicogenic headache. The GON orginates from the medial branch of the dorsal ramus of the C2 spinal nerve with variable contribution from the C3 dorsal ramus. After emerging from the suboccipital triangle, the nerve courses cephalad in an oblique trajectory between the semispinalis capitis (SC) and obliqus capitis inferior (OCI) muscles. This area was recognized as a potential location for GON injury. The nerve then passes through the trapezius muscle and courses medial to the occipital artery as it ascends to innervate the posterior scalp.

Many practitioners perform GON injections using a conventional approach, relying solely on superficial bone-based anatomic landmarks to infiltrate local anesthetic and corticosteroid around the nerve at the level of the superior nuchal line.

Some clinicians also use fluoroscopy to confirm the location of bony landmarks. The ambiguity of these injections poses a risk of anesthetizing adjacent structures or injecting into vessels, such as the occipital artery. Very limited research has been done to quantify the risk of these injections, but a complication rate of 5% to 10% has been reported, including headache, dizziness, blurred vision, and syncope.

Ultrasound guidance is increasingly used to mitigate these risks and improve the efficacy of GON injections. Multiple studies have demonstrated successful ultrasound-guided GON blockade at the superior nuchal line and improvement in pain scores compared with nonguided injections.

C2 level GON block using ultrasound targets interfascial plane between OCI and SC muscles. However, a pain physician who begins ultrasound guided injections migth feel very difficult targeting interfascial plane exactly.

Since GON orginiates from deep space of suboccipital triangle, it is expected that injection within OCI muscle might have similar effect with the effect of injection into interfascial plane.

We assume that if the local anesthetics is injected within OCI muscle, the effect of GON block will be generated by the diffusion of injected local anesthetics.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Cervicogenic headache
  • Migraine
  • Occipital neuralgia

Exclusion

Exclusion Criteria:

  • bilateral headache
  • cervical spine surgery within 1 year before
  • loss of sensory sensation at the dermatome of GON innervation
  • anatomical defect at the region of procedure
  • coagulopathy
  • pregnancy or breast feeding
  • allergy to local anesthetics

Study Design

Total Participants: 24
Treatment Group(s): 2
Primary Treatment: GON block
Phase:
Study Start date:
November 13, 2023
Estimated Completion Date:
June 30, 2024

Connect with a study center

  • Hong ji HEE

    Daegu, 42601
    Korea, Republic of

    Active - Recruiting

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