Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Atopic Dermatitis

Last updated: August 29, 2024
Sponsor: Escient Pharmaceuticals, Inc
Overall Status: Completed

Phase

2

Condition

Dermatitis, Atopic

Hives (Urticaria)

Skin Wounds

Treatment

Placebo

Oral EP262

Clinical Study ID

NCT06144424
EP-262-202
  • Ages 18-80
  • All Genders

Study Summary

This Phase 2a trial will evaluate the effects of EP262 in subjects with atopic dermatitis

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Clinically confirmed diagnosis of active atopic dermatitis for at least 1 year

  • BSA of 3% to 20% and a vIGA-AD score of ≥3

Exclusion

Exclusion Criteria:

  • Other active skin diseases associated with chronic pruritus

  • Clinically infected atopic dermatitis that requires antibiotic therapy

  • Use of specific treatments for atopic dermatitis

Study Design

Total Participants: 32
Treatment Group(s): 2
Primary Treatment: Placebo
Phase: 2
Study Start date:
October 25, 2023
Estimated Completion Date:
July 31, 2024

Connect with a study center

  • Innovaderm Research Inc.

    Montréal, Quebec H2X 2V1
    Canada

    Site Not Available

  • Allervie Clinical Research

    Birmingham, Alabama 35209
    United States

    Site Not Available

  • RM Medical Research, Inc.

    Miami Lakes, Florida 33014
    United States

    Site Not Available

  • Indiana Clinical Trials Center

    Plainfield, Indiana 46168
    United States

    Site Not Available

  • Lawrence J. Green, MD LLC

    Rockville, Maryland 20850
    United States

    Site Not Available

  • Revival Research Institute, LLC

    Troy, Michigan 48084
    United States

    Site Not Available

  • Optima Research Boardman

    Boardman, Ohio 44512
    United States

    Site Not Available

  • J&S Studies, Inc.

    College Station, Texas 77845
    United States

    Site Not Available

  • Jordan Valley Dermatology Center

    South Jordan, Utah 84095
    United States

    Site Not Available

  • Dermatology Specialists of Spokane

    Spokane, Washington 99202
    United States

    Site Not Available

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