Cholecalciferol and Calcifediol Are Both Useful to Improve Vitamin D Serum Levels

Last updated: November 20, 2025
Sponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Overall Status: Active - Recruiting

Phase

N/A

Condition

Bone Diseases

Treatment

Vitamin D

Clinical Study ID

NCT06138249
VITD
  • Ages 18-80
  • All Genders

Study Summary

Patients with hypovitaminosis D are randomized into three arms of treatment:

Group A: Calcifediol 0,266mg each month Group B: Cholecalciferol 25000UI each 15 days Group C: Calcifediol 4 drops per day. Serum levels of vitamin D are dosed after one month of treatment

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Hypovitaminosis D (<20ng/mL)

Exclusion

Exclusion Criteria:

  • Osteoporosis (T score <-2.5SD)

  • Renal or hepatic diseases

Study Design

Total Participants: 90
Treatment Group(s): 1
Primary Treatment: Vitamin D
Phase:
Study Start date:
July 01, 2023
Estimated Completion Date:
December 30, 2025

Study Description

Patients with hypovitaminosis D are randomized into three arms of treatment:

Group A: Calcifediol 0,266mg each month Group B: Cholecalciferol 25000UI each 15 days Group C: Calcifediol 4 drops per day. Serum levels of vitamin D are dosed after one month of treatment to support the best dosage of Vitamin D intake.

Connect with a study center

  • University of Bari

    Bari, 70124
    Italy

    Site Not Available

  • University of Bari

    Bari 3182351, 70124
    Italy

    Active - Recruiting

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