The Grief Navigation Trial: A Comparison of Two Interventions to Support Parents After Their Child's Unexpected or Traumatic Death

Last updated: April 28, 2025
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

CommunityRx-Bereavement

General Bereavement Support Information

Clinical Study ID

NCT06136260
2023-6458
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Parents of children who die traumatically or unexpectedly from things like suicide or an overdose suffer from mental and physical health problems and can experience massive disruptions in their family life. For about half of these parents, the first, and sometimes only, interactions they have with the healthcare system when their child dies are with a medical examiner or coroner (hereafter 'ME'). But MEs have little to no training in helping grieving families, and there are no standards guiding medical examiners or coroners on how or even if they should help grieving families. This gap leaves parents to find the help they need on their own. This research will test two different strategies for addressing this gap in the healthcare system.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Parents or caregivers of ME cases involving a person < 25 years old from one of thefollowing offices: Cook County Medical Examiners, Lake County Coroners, DuPageCounty Coroner, Will County Coroner, McHenry County Coroner, Kane County Coroner,Peoria County Coroner

  • Parents or caregivers who provide permission to the ME to be referred to MissingPieces

  • Parent or caregivers who are referred to Missing Pieces by a ME

  • Parents or caregivers able to read and communicate in English or Spanish

Exclusion

Exclusion Criteria:

  • Parents or caregivers unable to read or communicate in English or Spanish

  • Parents or caregivers under the age of 18 years old

Study Design

Total Participants: 2000
Treatment Group(s): 2
Primary Treatment: CommunityRx-Bereavement
Phase:
Study Start date:
March 04, 2024
Estimated Completion Date:
February 29, 2028

Study Description

Of approximately 60,000 annual deaths of people < 25 years old, ~45% occur unexpectedly or traumatically (e.g., from homicide, suicide, or unintentional injury) and become a medical examiner or coroner (hereafter 'ME') case. Parents and caregivers (hereafter 'parents') of these children suffer debilitating mental health issues like complicated grief and depression, physical problems and family dysfunction, and struggle to find support. Often, the ME is parents' sole point of contact with the healthcare system. Yet MEs have limited education, guidance, and tools to support bereaved parents. Scalable systems-level interventions are needed, at the point of ME care, to connect bereaved parents to critical supports.

This study will compare two interventions to facilitate care across healthcare settings for bereaved parents:

  1. CommunityRx-Bereavement (CRx-B), an evidence- and theory-based, low intensity, highly scalable intervention, and

  2. General bereavement support information (GBSI), a standardized treatment regimen developed from extant literature and current recommended standards for supporting parents after a child's death.

This is a pragmatic, multi-site 1:1 randomized controlled comparative effectiveness study using a type I hybrid design. CRx-B and GBSI will be carried out by Missing Pieces, a community-based organization. To learn about which strategy works better, the study team will ask parents to complete surveys ~6.5 months after their child dies.

Connect with a study center

  • Cook County Medical Examiner's Office

    Chicago, Illinois 60612
    United States

    Active - Recruiting

  • Will County Coroner's Office

    Joliet, Illinois 60432
    United States

    Active - Recruiting

  • Peoria County Coroner's Office

    Peoria, Illinois 61603
    United States

    Active - Recruiting

  • Kane County Coroner's Office

    Saint Charles, Illinois 60175
    United States

    Active - Recruiting

  • Lake County Coroner's Offic

    Waukegan, Illinois 60085
    United States

    Site Not Available

  • Lake County Coroner's Office

    Waukegan, Illinois 60085
    United States

    Active - Recruiting

  • DuPage County Coroner's Office

    Wheaton, Illinois 60187
    United States

    Active - Recruiting

  • McHenry County Coroner's Office

    Woodstock, Illinois 60098
    United States

    Active - Recruiting

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