A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Last updated: May 16, 2026
Sponsor: National Cancer Institute (NCI)
Overall Status: Active - Recruiting

Phase

2

Condition

Leukemia

Hematologic Cancer

Marginal Zone Lymphoma

Treatment

Echocardiography

Blinatumomab

Prednisolone

Clinical Study ID

NCT06124157
NCI-2023-09214
AALL2131
U10CA180886
NCI-2023-09214
  • Ages 366-46
  • All Genders

Study Summary

This pilot trial assesses the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (Ph+) or ABL-class Philadelphia chromosome-like (Ph-like) B-Cell acute lymphoblastic leukemia (B-ALL). Blinatumomab is a bispecific antibody that binds to two different proteins-one on the surface of cancer cells and one on the surface of cells in the immune system. An antibody is a protein made by the immune system to help fight infections and other harmful processes/cells/molecules. Blinatumomab may bind to the cancer cell and a T cell (which plays a key role in the immune system's fighting response) at the same time. Blinatumomab may strengthen the immune system's ability to fight cancer cells by activating the body's own immune cells to destroy the tumor. Dasatinib and imatinib are in a class of medications called tyrosine kinase inhibitors. They work by blocking the action of an abnormal protein that signals cancer cells to multiply, which may help keep cancer cells from growing. Giving blinatumomab and dasatinib or imatinib in combination with standard chemotherapy may work better in treating patients with Ph+ or Ph-like ABL-class B-ALL than dasatinib or imatinib with chemotherapy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients must be > 365 days and < 18 years (for AIEOP-BFM), > 365 days and < 22years (for Children's Oncology Group [COG]) and > 365 days and < 46 years (forALLTogether sites) at the time of enrollment

  • Newly-diagnosed Ph+ or ABL-class Ph-like B-ALL. Leukemic blasts must express CD19.ABL-class fusions are defined as rearrangements involving the following genespredicted to be sensitive to imatinib and/or dasatinib: ABL1, ABL2, CSF1R, andPDGFRB

  • Evidence of BCR::ABL1 should be documented by a clinically-validated assay prior tostudy entry on day 15 from the first dose of vinCRIStine during Induction therapy.ABL-class Ph-like B-ALL gene rearrangements should be documented by aclinically-validated assay and enrolled on study by day 1 of Blinatumomab Block 1.Accepted methods of detection include fluorescence in situ hybridization (FISH)using break-apart of colocalization signal probes, singleplex or multiplexreverse-transcription polymerase chain reaction (RT-PCR), whole-transcriptome orpanel-based ribonucleic acid (RNA) sequencing (e.g., Hematologic Cancer FusionAnalysis, TruSight RNA Pan-Cancer Panel or equivalent). Confirmation of 5' fusionpartner genes is not required for study enrollment

  • Patients with Ph+ B-ALL must have previously started Induction therapy, whichincludes vinCRIStine, a corticosteroid, pegaspargase or calaspargase pegol, with orwithout anthracycline, and/or other standard cytotoxic chemotherapy

  • Patients with Ph+ B-ALL have not received more than 14 days of systemic Inductiontherapy beginning with the first Induction dose of vinCRIStine

  • Patients with ABL-class Ph-like B-ALL must have previously completed 4 or 5 weeks ofmultiagent Induction chemotherapy (Induction 1A)

  • Patients may have started either imatinib or dasatinib prior to study entry butshould have received no more than 14 days of TKI for Ph+ B-ALL or no more than 35days of TKI for ABL-class Ph-like B-ALL

  • Patients must have a performance status corresponding to Eastern CooperativeOncology Group (ECOG) scores of ≤ 2 or Karnofsky and Lansky performance scores ≥ 50%. Use Karnofsky for patients > 16 years of age and Lansky for patients ≤ 16 yearsof age

  • For pediatric patients (age 1-17 years): a glomerular filtration rate (GFR) ≥ 50mL/min/1.73 m^2, as determined by one of the following methods (must be performedwithin 7 days prior to enrollment unless otherwise indicated):

  • Estimated GFR (eGFR) ≥ 50 mL/min/1.73 m2

  • Measured GFR ≥ 50 mL/min/1.73 m^2 (any age). If measured GFR is used, it mustbe performed using direct measurement with a nuclear blood sampling method orsmall molecule clearance method (iothalamate or other molecule perinstitutional standard

  • For adult patients (age 18 years or older): Creatinine clearance ≥ 30 mL/min, asestimated by the Cockcroft and Gault formula. The creatinine value used in thecalculation must have been obtained within 28 days prior to registration. Estimatedcreatinine clearance is based on body weight

  • Direct bilirubin < 2.0 mg/dL (34.2 micromoles/L) (must be performed within 7 daysprior to enrollment unless otherwise indicated)

  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 10 x upperlimit of normal (ULN) (must be performed within 7 days prior to enrollment unlessotherwise indicated)

    • Shortening fraction of ≥ 27% by echocardiogram (must be obtained within 21 daysprior to enrollment and start of protocol therapy [repeat if necessary]) OR

  • Left Ventricular Ejection fraction of ≥ 50% by radionuclide angiogram orechocardiogram (must be obtained within 21 days prior to enrollment and startof protocol therapy [repeat if necessary]) AND

  • Corrected QT Interval, QTc < 480mSec (must be obtained within 21 days prior toenrollment and start of protocol therapy [repeat if necessary])

  • Note: Repeat echocardiogram and electrocardiogram are not required if theywere performed at or after initial ALL diagnosis before study enrollment

Exclusion

Exclusion Criteria:

  • Known history of chronic myeloid leukemia (CML)

  • ABL-class Ph-like B-ALL who are CNS2 or CNS3 at end of Induction phase

  • ALL developing after a previous cancer treated with cytotoxic chemotherapy

  • Active, uncontrolled infection or active systemic illness that requires ongoingvasopressor support or mechanical ventilation

  • Down syndrome (trisomy 21)

  • Pregnancy and breast feeding

  • Female patients who are pregnant since fetal toxicities and teratogenic effectshave been noted for several of the study drugs. A negative pregnancy test isrequired for female patients of childbearing potential within 7 days prior toenrollment

  • Lactating females who plan to breastfeed their infants

  • Sexually active male and female patients of reproductive potential who have notagreed to use an effective contraception method for the duration of treatmentaccording to protocol

  • NOTE: Patients who could become pregnant or could father a child must useeffective contraception during protocol treatment and for 30 days afterthe last dose of dasatinib or 14 days after the last dose of imatinib doseor per institutional standard of care for multiagent chemotherapy,whichever is longer

  • Prior treatment with TKIs before study entry with the exception of imatinib ordasatinib

  • Patients with congenital long QT syndrome, history of ventricular arrhythmias, orheart block

  • Patients with known Charcot-Marie-Tooth disease

  • Patients with significant central nervous system pathology that would precludetreatment with blinatumomab, including history of severe neurologic disorder orautoimmune disease with central nervous system (CNS) involvement

  • Note: Patients with a history of seizures that are well controlled on stabledoses of anti-epileptic drugs are eligible. Patients with a history ofcerebrovascular ischemia/hemorrhage with residual deficits are not eligible.Patients with a history of cerebrovascular ischemia/hemorrhage remain eligibleprovided all neurologic deficits have resolved

  • HIV-infected patients are eligible if on effective anti-retroviral therapy that doesnot interact with planned study agents and with undetectable viral load within 6months of treatment

  • All patients and/or their parents or legal guardians must sign a written informedconsent

  • All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met

Study Design

Total Participants: 222
Treatment Group(s): 22
Primary Treatment: Echocardiography
Phase: 2
Study Start date:
May 30, 2025
Estimated Completion Date:
December 01, 2030

Study Description

PRIMARY OBJECTIVES:

I. To estimate the 3-year event free survival (EFS) of children, adolescents, and young adults <25 years old with newly-diagnosed Ph+ (BCR::ABL1-rearranged) B- ALL who are treated with a modified Berlin-Frankfurt-Münster (mBFM) chemotherapy backbone that incorporates three cycles of blinatumomab without traditional consolidation chemotherapy in combination with continuous dasatinib.

II. To estimate the 3-year EFS of children, adolescents, and young adults <25 years old with newly-diagnosed ABL-class Ph-like B-ALL who are treated with a modified BFM chemotherapy backbone that incorporates three cycles of blinatumomab without traditional consolidation chemotherapy in combination with continuous imatinib for those with PDGFRB gene fusions or dasatinib for those without PDGFRB gene fusions.

III. To describe the safety and toxicity profile (infections, mucositis, neurotoxicity, cytokine release syndrome, hypogammaglobulinemia, therapy delays > 14 days, and treatment-related mortality) for patients with Ph+ or ABL-class Ph-like B-ALL treated on this novel chemo-immunotherapy backbone with continuous tyrosine kinase inhibitor (TKI).

SECONDARY OBJECTIVES:

I. To estimate the 3-year overall survival (OS) of patients with Ph+ and ABL-class Ph-like B-ALL, respectively.

II. To estimate the 3-year EFS, disease-free survival (DFS), cumulative incidence rates (CIR) of relapse, and treatment related mortality (TRM), and OS of patients with ABL-class Ph-like B-ALL stratified by their underlying ABL-class fusion subtypes.

III. To describe rates of end of consolidation (EOC)/timepoint 2 (TP2) minimal residual disease (MRD) negativity defined as <1x10-4 or <0.01% for patients with Ph+ B-ALL.

IV. To describe rates of EOC/TP2 MRD negativity defined as <1x10-4 or <0.01% for patients with ABL-class Ph-like B-ALL collectively and based on their ABL-class fusion subtypes.

EXPLORATORY OBJECTIVES:

I. To describe rates of end of induction (EOI)/timepoint 1 (TP1) bone marrow MRD negativity defined as <1x10-4 or <0.01% with the introduction of the relevant TKI during Induction for patients with Ph+ and ABL-class Ph-like B-ALL, respectively.

II. To describe the outcomes of patients with Ph+ and ABL-class Ph-like B-ALL who are removed from protocol therapy due to Consolidation Failure.

III. To describe the percentage of patients with Ph+ and ABL-class Ph-like B-ALL who continue TKI beyond protocol-prescribed therapy and their outcomes.

IV. To describe the impact of MRD by next-generation sequencing (NGS) at End of Consolidation on outcomes for patients with Ph+ and ABL-class Ph-like B-ALL.

V. To describe the clinical characteristics and outcomes of patients with chronic myeloid leukemia-like biology.

VI. To describe the immune function of patients with Ph+ and ABL-class Ph-like B-ALL pre- and post-blinatumomab plus TKI and correlate with treatment response.

VII. To describe the TKI levels in the plasma and cerebrospinal fluid of children with Ph+ and ABL-class Ph-like B-ALL over the treatment course and correlate with outcome VIII. To describe the impact of TKIs and high-dose methotrexate interaction and identify clinical and biologic factors influencing methotrexate clearance.

OUTLINE:

STRATUM I (PH+ B-ALL PATIENTS):

INDUCTION PART I: Patients receive induction chemotherapy on days 1-14 as per standard of care (SOC).

INDUCTION PART II: Patients receive dasatinib PO once daily (QD) on days 15-29, daunorubicin intravenously (IV) over 15 minutes on days 15 and 22, prednisolone or prednisone PO twice daily (BID) on days 15-28, vincristine IV on days 15 and 22, methotrexate intrathecally (IT) on days 15, 22, and 29, and cytarabine IT on days 18 and 25 if central nervous system (CNS)-3 at study entry.

BLINATUMOMAB BLOCK I: Patients receive dexamethasone PO or intravenously (IV) on day 1, blinatumomab IV on days 1-28, dasatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study. Patients may undergo radiation therapy in 12 QD fractions.

BLINATUMOMAB BLOCK II: Patients receive dexamethasone PO or IV on day 1, blinatumomab IV on days 1-28, dasatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study.

INTERIM MAINTENANCE I: Patients receive dasatinib PO QD until the end of interim maintenance I, mercaptopurine PO QD on days 1-56, vincristine IV on days 8, 22, 36, and 50, methotrexate IT on days 8 and 36, high-dose methotrexate IV over 24 hours on days 8, 22, 36 and 50, and leucovorin PO or IV on days 10, 11, 24, 25, 38, 39, 52 and 53 over 9 weeks on study.

BLINATUMOMAB BLOCK III: Patients receive blinatumomab IV on days 1-28, dasatinib PO QD on days 1-35, and methotrexate IT on day 1 over 5 weeks on study.

DELAYED INTENSIFICATION PART I: Patients receive dasatinib PO QD on days 1-28, methotrexate IT on day 1, dexamethasone PO or IV on days 1-7 and 15-21, doxorubicin IV over 15 minutes on days 1, 8, and 15, vincristine IV on days 1, 8, and 15, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on day 4 over 4 weeks on study.

DELAYED INTENSIFICATION PART II: Patients receive dasatinib PO QD on day 29 until the end of delayed intensification part II, cyclophosphamide IV over 60 minutes on day 29, cytarabine IV over 30 minutes on days 29-32 and 36-39, methotrexate IT on days 29 and 36, thioguanine PO on days 29-42, pegaspargase IV or calaspargase pegol on day 43 and vincristine IV on days 43 and 50 over 5 weeks on study.

INTERIM MAINTENANCE PART II: Patients receive dasatinib PO QD on day 1 until the end of interim maintenance part II, methotrexate IV on days 1, 11, 21, 31, and 41, vincristine IV on 1, 11, 21, 31, and 41, methotrexate IT on days 1 and 31, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on days 2, 22 or 23 over 8 weeks on study.

MAINTENANCE CYCLES I-II: Patients receive dasatinib PO QD on days 1-84, methotrexate IT on days 1 and 29, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study.

MAINTENANCE CYCLES III AND SUBSEQUENT CYCLES: Patients receive dasatinib PO QD on days 1-84, methotrexate IT on day 1, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study. Cycles repeat every 12 weeks for 2 years from the start of Induction therapy in the absence of disease progression or unacceptable toxicity.

STRATUM II (PDGFRB ABL-CLASS FUSIONS):

BLINATUMOMAB BLOCK I: Patients receive dexamethasone PO or IV on day 1, blinatumomab IV on days 1-28, imatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study. Patients may undergo radiation therapy in 12 QD fractions.

BLINATUMOMAB BLOCK II: Patients receive dexamethasone PO or IV on day 1, blinatumomab IV on days 1-28, imatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study.

INTERIM MAINTENANCE I: Patients receive imatinib PO QD until the end of interim maintenance I, mercaptopurine PO QD on days 1-56, vincristine IV on days 8, 22, 36, and 50, methotrexate IT on days 8 and 36, high-dose methotrexate IV over 24 hours on days 8, 22, 36 and 50, and leucovorin PO or IV on days 10, 11, 24, 25, 38, 39, 52 and 53 over 9 weeks on study.

BLINATUMOMAB BLOCK III: Patients receive blinatumomab IV on days 1-28, imatinib PO QD on days 1-35, and methotrexate IT on day 1 over 5 weeks on study.

DELAYED INTENSIFICATION PART I: Patients receive imatinib PO QD on days 1-28, methotrexate IT on day 1, dexamethasone PO or IV on days 1-7 and 15-21, doxorubicin IV over 15 minutes on days 1, 8, and 15, vincristine IV on days 1, 8, and 15, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on day 4 over 9 weeks on study.

DELAYED INTENSIFICATION PART II: Patients receive imatinib PO QD on day 29 until the end of Delayed Intensification part II, cyclophosphamide IV over 30-60 minutes on day 29, cytarabine IV over 30 minutes on days 29-32 and 36-39, methotrexate IT on days 29 and 36, thioguanine PO on days 29-42, and pegaspargase IV or calaspargase pegol IV on day 43, and vincristine IV on days 43 and 50 over 5 weeks on study.

INTERIM MAINTENANCE II: Patients receive imatinib PO QD until the end of interim maintenance II, methotrexate IV and vincristine IV on days 1, 11, 21, 31 and 41, methotrexate IT on days 1 and 31, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on days 2, 22 or 23 over 8 weeks on study.

MAINTENANCE CYCLES I-II: Patients receive imatinib PO QD on days 1-84, methotrexate IT on days 1 and 29, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study.

MAINTENANCE CYCLES III AND SUBSEQUENT CYCLES: Patients receive imatinib PO QD on days 1-84, methotrexate IT on day 1, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study. Cycles repeat every 12 weeks for 2 years from the start of Induction therapy in the absence of disease progression or unacceptable toxicity.

STRATUM III (NON-PDGFRB ABL-CLASS FUSIONS):

BLINATUMOMAB BLOCK I: Patients receive dexamethasone PO or IV on day 1, blinatumomab IV on days 1-28, dasatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study. Patients may undergo radiation therapy in 12 QD fractions.

BLINATUMOMAB BLOCK II: Patients receive dexamethasone PO or IV on day 1, blinatumomab IV on days 1-28, dasatinib PO on days 1-35, and methotrexate IT on days 1 and 15 over 5 weeks on study.

INTERIM MAINTENANCE I: Patients receive dasatinib PO QD until the end of interim maintenance I, mercaptopurine PO QD on days 1-56, vincristine IV on days 8, 22, 36, and 50, methotrexate IT on days 8 and 36, high-dose methotrexate IV over 24 hours on days 8, 22, 36 and 50, and leucovorin PO or IV on days 10, 11, 24, 25, 38, 39, 52 and 53 over 9 weeks on study.

BLINATUMOMAB BLOCK III: Patients receive blinatumomab IV on days 1-28, dasatinib PO on days 1-35, and methotrexate IT on day 1 over 5 weeks on study.

DELAYED INTENSIFICATION PART I: Patients receive dasatinib PO QD on days 1-28, methotrexate IT on day 1, dexamethasone PO or IV on days 1-7 and 15-21, doxorubicin IV over 15 minutes on days 1, 8, and 15, vincristine IV on days 1, 8, and 15, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on day 4 over 4 weeks on study.

DELAYED INTENSIFICATION PART II: Patients receive dasatinib PO QD and methotrexate IT on day 29 until the end of Delayed Intensification part II, cyclophosphamide IV over 30-60 minutes on day 29, cytarabine IV over 30 minutes on days 29-32 and 36-39, methotrexate IT on days 29 and 36, thioguanine PO on days 29-42, pegaspargase IV or calaspargase pegol on day 43 and vincristine IV on days 43 and 50 over 5 weeks on study.

INTERIM MAINTENANCE II: Patients receive dasatinib PO QD until the end of interim maintenance II, methotrexate IV and vincristine IV on days 1, 11, 21, 31 and 41, methotrexate IT on days 1 and 31, and pegaspargase IV or calaspargase pegol IV over 1-2 hours on days 2, 22 or 23 over 8 weeks on study.

MAINTENANCE CYCLES I-II: Patients receive dasatinib PO QD on days 1-84, methotrexate IT on days 1 and 29, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study.

MAINTENANCE CYCLES III AND SUBSEQUENT CYCLES: Patients receive dasatinib PO QD on days 1-84, methotrexate IT on day 1, dexamethasone PO BID or IV on days 1-5, 29-33, and 57-61, mercaptopurine PO on days 1-84, vincristine IV on days 1, 29 and 57, and methotrexate PO on days 8, 15, 22, 29, 36, 43, 50, 57, 64, 71, and 78 on study. Cycles repeat every 12 weeks for 2 years from the start of Induction therapy in the absence of disease progression or unacceptable toxicity.

All patients undergo echocardiography (ECHO) or multigated acquisition scan (MUGA) during screening. Patients also undergo blood and cerebrospinal fluid (CSF) sample collection and bone marrow biopsy throughout the study and as clinically indicated on study.

Connect with a study center

  • Queensland Children's Hospital

    South Brisbane, Queensland 4101
    Australia

    Active - Recruiting

  • Queensland Children's Hospital

    South Brisbane 2207259, Queensland 2152274 4101
    Australia

    Site Not Available

  • Perth Children's Hospital

    Perth, Western Australia 6009
    Australia

    Active - Recruiting

  • Perth Children's Hospital

    Perth 2063523, Western Australia 2058645 6009
    Australia

    Site Not Available

  • Alberta Children's Hospital

    Calgary, Alberta T3B 6A8
    Canada

    Active - Recruiting

  • British Columbia Children's Hospital

    Vancouver, British Columbia V6H 3V4
    Canada

    Suspended

  • British Columbia Children's Hospital

    Vancouver 6173331, British Columbia 5909050 V6H 3V4
    Canada

    Site Not Available

  • CancerCare Manitoba

    Winnipeg, Manitoba R3E 0V9
    Canada

    Active - Recruiting

  • IWK Health Centre

    Halifax, Nova Scotia B3K 6R8
    Canada

    Active - Recruiting

  • IWK Health Centre

    Halifax 6324729, Nova Scotia 6091530 B3K 6R8
    Canada

    Site Not Available

  • McMaster Children's Hospital at Hamilton Health Sciences

    Hamilton, Ontario L8N 3Z5
    Canada

    Active - Recruiting

  • Hospital for Sick Children

    Toronto, Ontario M5G 1X8
    Canada

    Active - Recruiting

  • McMaster Children's Hospital at Hamilton Health Sciences

    Hamilton 5969782, Ontario 6093943 L8N 3Z5
    Canada

    Site Not Available

  • Hospital for Sick Children

    Toronto 6167865, Ontario 6093943 M5G 1X8
    Canada

    Site Not Available

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec H3T 1C5
    Canada

    Active - Recruiting

  • The Montreal Children's Hospital of the MUHC

    Montreal, Quebec H3H 1P3
    Canada

    Active - Recruiting

  • Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

    Sherbrooke, Quebec J1H 5N4
    Canada

    Active - Recruiting

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal 6077243, Quebec 6115047 H3T 1C5
    Canada

    Suspended

  • The Montreal Children's Hospital of the MUHC

    Montreal 6077243, Quebec 6115047 H3H 1P3
    Canada

    Site Not Available

  • Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

    Sherbrooke 6146143, Quebec 6115047 J1H 5N4
    Canada

    Site Not Available

  • CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL)

    Québec, G1V 4G2
    Canada

    Active - Recruiting

  • CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL)

    Québec 6325494, G1V 4G2
    Canada

    Site Not Available

  • University Pediatric Hospital

    San Juan, 00926
    Puerto Rico

    Active - Recruiting

  • University Pediatric Hospital

    San Juan 4568127, 00926
    Puerto Rico

    Site Not Available

  • Children's Hospital of Alabama

    Birmingham, Alabama 35233
    United States

    Active - Recruiting

  • Children's Hospital of Alabama

    Birmingham 4049979, Alabama 4829764 35233
    United States

    Site Not Available

  • Phoenix Childrens Hospital

    Phoenix, Arizona 85016
    United States

    Active - Recruiting

  • Banner University Medical Center - Tucson

    Tucson, Arizona 85719
    United States

    Active - Recruiting

  • Phoenix Childrens Hospital

    Phoenix 5308655, Arizona 5551752 85016
    United States

    Site Not Available

  • Arkansas Children's Hospital

    Little Rock, Arkansas 72202-3591
    United States

    Active - Recruiting

  • Arkansas Children's Hospital

    Little Rock 4119403, Arkansas 4099753 72202-3591
    United States

    Site Not Available

  • Loma Linda University Medical Center

    Loma Linda, California 92354
    United States

    Active - Recruiting

  • Miller Children's and Women's Hospital Long Beach

    Long Beach, California 90806
    United States

    Active - Recruiting

  • Children's Hospital Los Angeles

    Los Angeles, California 90027
    United States

    Active - Recruiting

  • Valley Children's Hospital

    Madera, California 93636
    United States

    Active - Recruiting

  • Kaiser Permanente-Oakland

    Oakland, California 94611
    United States

    Active - Recruiting

  • UCSF Benioff Children's Hospital Oakland

    Oakland, California 94609
    United States

    Active - Recruiting

  • Children's Hospital of Orange County

    Orange, California 92868
    United States

    Active - Recruiting

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto, California 94304
    United States

    Active - Recruiting

  • Rady Children's Hospital - San Diego

    San Diego, California 92123
    United States

    Active - Recruiting

  • UCSF Medical Center-Mission Bay

    San Francisco, California 94158
    United States

    Active - Recruiting

  • Loma Linda University Medical Center

    Loma Linda 5367696, California 5332921 92354
    United States

    Site Not Available

  • Miller Children's and Women's Hospital Long Beach

    Long Beach 5367929, California 5332921 90806
    United States

    Site Not Available

  • Children's Hospital Los Angeles

    Los Angeles 5368361, California 5332921 90027
    United States

    Site Not Available

  • Kaiser Permanente-Oakland

    Oakland 5378538, California 5332921 94611
    United States

    Active - Recruiting

  • UCSF Benioff Children's Hospital Oakland

    Oakland 5378538, California 5332921 94609
    United States

    Site Not Available

  • Children's Hospital of Orange County

    Orange 5379513, California 5332921 92868
    United States

    Site Not Available

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto 5380748, California 5332921 94304
    United States

    Site Not Available

  • Rady Children's Hospital - San Diego

    San Diego 5391811, California 5332921 92123
    United States

    Site Not Available

  • UCSF Medical Center-Mission Bay

    San Francisco 5391959, California 5332921 94158
    United States

    Site Not Available

  • Children's Hospital Colorado

    Aurora, Colorado 80045
    United States

    Active - Recruiting

  • Children's Hospital Colorado

    Aurora 5412347, Colorado 5417618 80045
    United States

    Site Not Available

  • Connecticut Children's Medical Center

    Hartford, Connecticut 06106
    United States

    Active - Recruiting

  • Yale University

    New Haven, Connecticut 06520
    United States

    Active - Recruiting

  • Yale University

    New Haven 4839366, Connecticut 4831725 06520
    United States

    Site Not Available

  • Alfred I duPont Hospital for Children

    Wilmington, Delaware 19803
    United States

    Active - Recruiting

  • Alfred I duPont Hospital for Children

    Wilmington 4145381, Delaware 4142224 19803
    United States

    Site Not Available

  • Children's National Medical Center

    Washington D.C., District of Columbia 20010
    United States

    Active - Recruiting

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia 20007
    United States

    Active - Recruiting

  • Children's National Medical Center

    Washington D.C. 4140963, District of Columbia 4138106 20010
    United States

    Active - Recruiting

  • MedStar Georgetown University Hospital

    Washington D.C. 4140963, District of Columbia 4138106 20007
    United States

    Site Not Available

  • Golisano Children's Hospital of Southwest Florida

    Fort Myers, Florida 33908
    United States

    Active - Recruiting

  • UF Health Cancer Institute - Gainesville

    Gainesville, Florida 32610
    United States

    Active - Recruiting

  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital

    Hollywood, Florida 33021
    United States

    Active - Recruiting

  • Nemours Children's Clinic-Jacksonville

    Jacksonville, Florida 32207
    United States

    Active - Recruiting

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida 33136
    United States

    Active - Recruiting

  • Arnold Palmer Hospital for Children

    Orlando, Florida 32806
    United States

    Active - Recruiting

  • Nemours Children's Hospital

    Orlando, Florida 32827
    United States

    Active - Recruiting

  • Nemours Children's Clinic - Pensacola

    Pensacola, Florida 32504
    United States

    Active - Recruiting

  • Johns Hopkins All Children's Hospital

    St. Petersburg, Florida 33701
    United States

    Active - Recruiting

  • Saint Joseph's Hospital/Children's Hospital-Tampa

    Tampa, Florida 33607
    United States

    Active - Recruiting

  • Saint Mary's Medical Center

    West Palm Beach, Florida 33407
    United States

    Active - Recruiting

  • Golisano Children's Hospital of Southwest Florida

    Fort Myers 4155995, Florida 4155751 33908
    United States

    Site Not Available

  • UF Health Cancer Institute - Gainesville

    Gainesville 4156404, Florida 4155751 32610
    United States

    Site Not Available

  • University of Florida Health Science Center - Gainesville

    Gainesville 4156404, Florida 4155751 32610
    United States

    Active - Recruiting

  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital

    Hollywood 4158928, Florida 4155751 33021
    United States

    Site Not Available

  • Nemours Children's Clinic-Jacksonville

    Jacksonville 4160021, Florida 4155751 32207
    United States

    Site Not Available

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami 4164138, Florida 4155751 33136
    United States

    Site Not Available

  • Arnold Palmer Hospital for Children

    Orlando 4167147, Florida 4155751 32806
    United States

    Site Not Available

  • Nemours Children's Clinic - Pensacola

    Pensacola 4168228, Florida 4155751 32504
    United States

    Site Not Available

  • Johns Hopkins All Children's Hospital

    St. Petersburg 4171563, Florida 4155751 33701
    United States

    Site Not Available

  • Saint Joseph's Hospital/Children's Hospital-Tampa

    Tampa 4174757, Florida 4155751 33607
    United States

    Site Not Available

  • Saint Mary's Medical Center

    West Palm Beach 4177887, Florida 4155751 33407
    United States

    Site Not Available

  • Children's Healthcare of Atlanta - Arthur M Blank Hospital

    Atlanta, Georgia 30329
    United States

    Active - Recruiting

  • Augusta University Medical Center

    Augusta, Georgia 30912
    United States

    Active - Recruiting

  • Atrium Health Navicent

    Macon, Georgia 31201
    United States

    Active - Recruiting

  • Memorial Health University Medical Center

    Savannah, Georgia 31404
    United States

    Active - Recruiting

  • Children's Healthcare of Atlanta - Arthur M Blank Hospital

    Atlanta 4180439, Georgia 4197000 30329
    United States

    Site Not Available

  • Augusta University Medical Center

    Augusta 4180531, Georgia 4197000 30912
    United States

    Site Not Available

  • Atrium Health Navicent

    Macon 4207400, Georgia 4197000 31201
    United States

    Site Not Available

  • Memorial Health University Medical Center

    Savannah 4221552, Georgia 4197000 31404
    United States

    Site Not Available

  • Kapiolani Medical Center for Women and Children

    Honolulu, Hawaii 96826
    United States

    Active - Recruiting

  • Kapiolani Medical Center for Women and Children

    Honolulu 5856195, Hawaii 5855797 96826
    United States

    Site Not Available

  • Saint Luke's Cancer Institute - Boise

    Boise, Idaho 83712
    United States

    Active - Recruiting

  • Saint Luke's Cancer Institute - Boise

    Boise 5586437, Idaho 5596512 83712
    United States

    Site Not Available

  • Lurie Children's Hospital-Chicago

    Chicago, Illinois 60611
    United States

    Active - Recruiting

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois 60637
    United States

    Active - Recruiting

  • University of Illinois

    Chicago, Illinois 60612
    United States

    Active - Recruiting

  • Advocate Children's Hospital-Oak Lawn

    Oak Lawn, Illinois 60453
    United States

    Active - Recruiting

  • Advocate Children's Hospital-Park Ridge

    Park Ridge, Illinois 60068
    United States

    Active - Recruiting

  • Saint Jude Midwest Affiliate

    Peoria, Illinois 61637
    United States

    Active - Recruiting

  • Southern Illinois University School of Medicine

    Springfield, Illinois 62702
    United States

    Active - Recruiting

  • Lurie Children's Hospital-Chicago

    Chicago 4887398, Illinois 4896861 60611
    United States

    Active - Recruiting

  • University of Chicago Comprehensive Cancer Center

    Chicago 4887398, Illinois 4896861 60637
    United States

    Active - Recruiting

  • University of Illinois

    Chicago 4887398, Illinois 4896861 60612
    United States

    Site Not Available

  • Advocate Children's Hospital-Oak Lawn

    Oak Lawn 4904365, Illinois 4896861 60453
    United States

    Site Not Available

  • Advocate Children's Hospital-Park Ridge

    Park Ridge 4905367, Illinois 4896861 60068
    United States

    Site Not Available

  • Southern Illinois University School of Medicine

    Springfield 4250542, Illinois 4896861 62702
    United States

    Site Not Available

  • Riley Hospital for Children

    Indianapolis, Indiana 46202
    United States

    Active - Recruiting

  • Riley Hospital for Children

    Indianapolis 4259418, Indiana 4921868 46202
    United States

    Site Not Available

  • Blank Children's Hospital

    Des Moines, Iowa 50309
    United States

    Active - Recruiting

  • University of Iowa/Holden Comprehensive Cancer Center

    Iowa City, Iowa 52242
    United States

    Active - Recruiting

  • University of Iowa/Holden Comprehensive Cancer Center

    Iowa City 4862034, Iowa 4862182 52242
    United States

    Site Not Available

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky 40536
    United States

    Active - Recruiting

  • University of Kentucky/Markey Cancer Center

    Lexington 4297983, Kentucky 6254925 40536
    United States

    Site Not Available

  • Ochsner Medical Center Jefferson

    New Orleans, Louisiana 70121
    United States

    Active - Recruiting

  • Ochsner Medical Center Jefferson

    New Orleans 4335045, Louisiana 4331987 70121
    United States

    Site Not Available

  • Maine Children's Cancer Program

    Scarborough, Maine 04074
    United States

    Active - Recruiting

  • Maine Children's Cancer Program

    Scarborough 4977882, Maine 4971068 04074
    United States

    Site Not Available

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland 21287
    United States

    Active - Recruiting

  • Sinai Hospital of Baltimore

    Baltimore, Maryland 21215
    United States

    Active - Recruiting

  • Walter Reed National Military Medical Center

    Bethesda, Maryland 20889-5600
    United States

    Active - Recruiting

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore 4347778, Maryland 4361885 21287
    United States

    Active - Recruiting

  • Sinai Hospital of Baltimore

    Baltimore 4347778, Maryland 4361885 21215
    United States

    Site Not Available

  • Walter Reed National Military Medical Center

    Bethesda 4348599, Maryland 4361885 20889-5600
    United States

    Site Not Available

  • Dana-Farber Cancer Institute

    Boston, Massachusetts 02215
    United States

    Active - Recruiting

  • UMass Memorial Medical Center - University Campus

    Worcester, Massachusetts 01655
    United States

    Active - Recruiting

  • Dana-Farber Cancer Institute

    Boston 4930956, Massachusetts 6254926 02215
    United States

    Site Not Available

  • UMass Memorial Medical Center - University Campus

    Worcester 4956184, Massachusetts 6254926 01655
    United States

    Site Not Available

  • C S Mott Children's Hospital

    Ann Arbor, Michigan 48109
    United States

    Active - Recruiting

  • Children's Hospital of Michigan

    Detroit, Michigan 48201
    United States

    Active - Recruiting

  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

    Grand Rapids, Michigan 49503
    United States

    Active - Recruiting

  • Bronson Methodist Hospital

    Kalamazoo, Michigan 49007
    United States

    Active - Recruiting

  • C S Mott Children's Hospital

    Ann Arbor 4984247, Michigan 5001836 48109
    United States

    Site Not Available

  • Children's Hospital of Michigan

    Detroit 4990729, Michigan 5001836 48201
    United States

    Site Not Available

  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

    Grand Rapids 4994358, Michigan 5001836 49503
    United States

    Site Not Available

  • Bronson Methodist Hospital

    Kalamazoo 4997787, Michigan 5001836 49007
    United States

    Site Not Available

  • Children's Hospitals and Clinics of Minnesota - Minneapolis

    Minneapolis, Minnesota 55404
    United States

    Active - Recruiting

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota 55455
    United States

    Active - Recruiting

  • Mayo Clinic in Rochester

    Rochester, Minnesota 55905
    United States

    Active - Recruiting

  • University of Minnesota/Masonic Cancer Center

    Minneapolis 5037649, Minnesota 5037779 55455
    United States

    Site Not Available

  • Mayo Clinic in Rochester

    Rochester 5043473, Minnesota 5037779 55905
    United States

    Site Not Available

  • University of Mississippi Medical Center

    Jackson, Mississippi 39216
    United States

    Active - Recruiting

  • University of Mississippi Medical Center

    Jackson 4431410, Mississippi 4436296 39216
    United States

    Site Not Available

  • Children's Mercy Hospitals and Clinics

    Kansas City, Missouri 64108
    United States

    Active - Recruiting

  • Washington University School of Medicine

    St Louis, Missouri 63110
    United States

    Active - Recruiting

  • Children's Mercy Hospitals and Clinics

    Kansas City 4393217, Missouri 4398678 64108
    United States

    Site Not Available

  • Washington University School of Medicine

    St Louis 4407066, Missouri 4398678 63110
    United States

    Site Not Available

  • Children's Hospital and Medical Center of Omaha

    Omaha, Nebraska 68114
    United States

    Active - Recruiting

  • Children's Hospital and Medical Center of Omaha

    Omaha 5074472, Nebraska 5073708 68114
    United States

    Site Not Available

  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation

    Las Vegas, Nevada 89135
    United States

    Active - Recruiting

  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation

    Las Vegas 5506956, Nevada 5509151 89135
    United States

    Site Not Available

  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

    Lebanon, New Hampshire 03756
    United States

    Active - Recruiting

  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

    Lebanon 5088597, New Hampshire 5090174 03756
    United States

    Site Not Available

  • Hackensack University Medical Center

    Hackensack, New Jersey 07601
    United States

    Active - Recruiting

  • Morristown Medical Center

    Morristown, New Jersey 07960
    United States

    Active - Recruiting

  • Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital

    New Brunswick, New Jersey 08903
    United States

    Active - Recruiting

  • Saint Joseph's Regional Medical Center

    Paterson, New Jersey 07503
    United States

    Active - Recruiting

  • Hackensack University Medical Center

    Hackensack 5098706, New Jersey 5101760 07601
    United States

    Site Not Available

  • Morristown Medical Center

    Morristown 5101427, New Jersey 5101760 07960
    United States

    Site Not Available

  • Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital

    New Brunswick 5101717, New Jersey 5101760 08903
    United States

    Site Not Available

  • Saint Joseph's Regional Medical Center

    Paterson 5102466, New Jersey 5101760 07503
    United States

    Site Not Available

  • University of New Mexico Cancer Center

    Albuquerque, New Mexico 87106
    United States

    Active - Recruiting

  • Albany Medical Center

    Albany, New York 12208
    United States

    Active - Recruiting

  • Roswell Park Cancer Institute

    Buffalo, New York 14263
    United States

    Active - Recruiting

  • NYU Langone Hospital - Long Island

    Mineola, New York 11501
    United States

    Active - Recruiting

  • The Steven and Alexandra Cohen Children's Medical Center of New York

    New Hyde Park, New York 11040
    United States

    Active - Recruiting

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York 10016
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center

    New York, New York 10065
    United States

    Active - Recruiting

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    New York, New York 10032
    United States

    Active - Recruiting

  • NYP/Weill Cornell Medical Center

    New York, New York 10065
    United States

    Active - Recruiting

  • Stony Brook University Medical Center

    Stony Brook, New York 11794
    United States

    Active - Recruiting

  • State University of New York Upstate Medical University

    Syracuse, New York 13210
    United States

    Active - Recruiting

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York 10467
    United States

    Active - Recruiting

  • New York Medical College

    Valhalla, New York 10595
    United States

    Active - Recruiting

  • Albany Medical Center

    Albany 5106834, New York 5128638 12208
    United States

    Site Not Available

  • Roswell Park Cancer Institute

    Buffalo 5110629, New York 5128638 14263
    United States

    Site Not Available

  • NYU Langone Hospital - Long Island

    Mineola 5127134, New York 5128638 11501
    United States

    Site Not Available

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York 5128581, New York 5128638 10016
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center

    New York 5128581, New York 5128638 10065
    United States

    Active - Recruiting

  • NYP/Weill Cornell Medical Center

    New York 5128581, New York 5128638 10065
    United States

    Site Not Available

  • Stony Brook University Medical Center

    Stony Brook 5139865, New York 5128638 11794
    United States

    Site Not Available

  • State University of New York Upstate Medical University

    Syracuse 5140405, New York 5128638 13210
    United States

    Site Not Available

  • New York Medical College

    Valhalla 5142090, New York 5128638 10595
    United States

    Site Not Available

  • Mission Hospital

    Asheville, North Carolina 28801
    United States

    Active - Recruiting

  • Carolinas Medical Center/Levine Cancer Institute

    Charlotte, North Carolina 28203
    United States

    Active - Recruiting

  • Duke University Medical Center

    Durham, North Carolina 27710
    United States

    Active - Recruiting

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina 27157
    United States

    Active - Recruiting

  • Mission Hospital

    Asheville 4453066, North Carolina 4482348 28801
    United States

    Site Not Available

  • Carolinas Medical Center/Levine Cancer Institute

    Charlotte 4460243, North Carolina 4482348 28203
    United States

    Site Not Available

  • Duke University Medical Center

    Durham 4464368, North Carolina 4482348 27710
    United States

    Site Not Available

  • Wake Forest University Health Sciences

    Winston-Salem 4499612, North Carolina 4482348 27157
    United States

    Site Not Available

  • Sanford Broadway Medical Center

    Fargo, North Dakota 58122
    United States

    Active - Recruiting

  • Children's Hospital Medical Center of Akron

    Akron, Ohio 44308
    United States

    Active - Recruiting

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio 45229
    United States

    Active - Recruiting

  • Rainbow Babies and Childrens Hospital

    Cleveland, Ohio 44106
    United States

    Active - Recruiting

  • Nationwide Children's Hospital

    Columbus, Ohio 43205
    United States

    Active - Recruiting

  • Dayton Children's Hospital

    Dayton, Ohio 45404
    United States

    Active - Recruiting

  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

    Toledo, Ohio 43606
    United States

    Active - Recruiting

  • Children's Hospital Medical Center of Akron

    Akron 5145476, Ohio 5165418 44308
    United States

    Site Not Available

  • Cincinnati Children's Hospital Medical Center

    Cincinnati 4508722, Ohio 5165418 45229
    United States

    Site Not Available

  • Rainbow Babies and Childrens Hospital

    Cleveland 5150529, Ohio 5165418 44106
    United States

    Site Not Available

  • Nationwide Children's Hospital

    Columbus 4509177, Ohio 5165418 43205
    United States

    Site Not Available

  • Dayton Children's Hospital

    Dayton 4509884, Ohio 5165418 45404
    United States

    Site Not Available

  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

    Toledo 5174035, Ohio 5165418 43606
    United States

    Site Not Available

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma 73104
    United States

    Active - Recruiting

  • University of Oklahoma Health Sciences Center

    Oklahoma City 4544349, Oklahoma 4544379 73104
    United States

    Site Not Available

  • Lehigh Valley Hospital-Cedar Crest

    Allentown, Pennsylvania 18103
    United States

    Active - Recruiting

  • Penn State Children's Hospital

    Hershey, Pennsylvania 17033
    United States

    Active - Recruiting

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania 19104
    United States

    Active - Recruiting

  • Saint Christopher's Hospital for Children

    Philadelphia, Pennsylvania 19134
    United States

    Active - Recruiting

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania 15224
    United States

    Active - Recruiting

  • Lehigh Valley Hospital-Cedar Crest

    Allentown 5178127, Pennsylvania 6254927 18103
    United States

    Site Not Available

  • Penn State Children's Hospital

    Hershey 5193342, Pennsylvania 6254927 17033
    United States

    Site Not Available

  • Children's Hospital of Philadelphia

    Philadelphia 4560349, Pennsylvania 6254927 19104
    United States

    Site Not Available

  • Saint Christopher's Hospital for Children

    Philadelphia 4560349, Pennsylvania 6254927 19134
    United States

    Active - Recruiting

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh 5206379, Pennsylvania 6254927 15224
    United States

    Site Not Available

  • Rhode Island Hospital

    Providence, Rhode Island 02903
    United States

    Active - Recruiting

  • Rhode Island Hospital

    Providence 5224151, Rhode Island 5224323 02903
    United States

    Site Not Available

  • Prisma Health Richland Hospital

    Columbia, South Carolina 29203
    United States

    Active - Recruiting

  • BI-LO Charities Children's Cancer Center

    Greenville, South Carolina 29605
    United States

    Active - Recruiting

  • Prisma Health Richland Hospital

    Columbia 4575352, South Carolina 4597040 29203
    United States

    Site Not Available

  • BI-LO Charities Children's Cancer Center

    Greenville 4580543, South Carolina 4597040 29605
    United States

    Site Not Available

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota 57117-5134
    United States

    Active - Recruiting

  • East Tennessee Childrens Hospital

    Knoxville, Tennessee 37916
    United States

    Active - Recruiting

  • The Children's Hospital at TriStar Centennial

    Nashville, Tennessee 37203
    United States

    Active - Recruiting

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee 37232
    United States

    Active - Recruiting

  • East Tennessee Childrens Hospital

    Knoxville 4634946, Tennessee 4662168 37916
    United States

    Site Not Available

  • The Children's Hospital at TriStar Centennial

    Nashville 4644585, Tennessee 4662168 37203
    United States

    Active - Recruiting

  • Vanderbilt University/Ingram Cancer Center

    Nashville 4644585, Tennessee 4662168 37232
    United States

    Site Not Available

  • Dell Children's Medical Center of Central Texas

    Austin, Texas 78723
    United States

    Active - Recruiting

  • Driscoll Children's Hospital

    Corpus Christi, Texas 78411
    United States

    Active - Recruiting

  • Medical City Dallas Hospital

    Dallas, Texas 75230
    United States

    Active - Recruiting

  • UT Southwestern/Simmons Cancer Center-Dallas

    Dallas, Texas 75390
    United States

    Active - Recruiting

  • El Paso Children's Hospital

    El Paso, Texas 79905
    United States

    Active - Recruiting

  • Cook Children's Medical Center

    Fort Worth, Texas 76104
    United States

    Active - Recruiting

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

  • Covenant Children's Hospital

    Lubbock, Texas 79410
    United States

    Active - Recruiting

  • UMC Cancer Center / UMC Health System

    Lubbock, Texas 79415
    United States

    Active - Recruiting

  • Children's Hospital of San Antonio

    San Antonio, Texas 78207
    United States

    Active - Recruiting

  • Methodist Children's Hospital of South Texas

    San Antonio, Texas 78229
    United States

    Active - Recruiting

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas 78229
    United States

    Active - Recruiting

  • Dell Children's Medical Center of Central Texas

    Austin 4671654, Texas 4736286 78723
    United States

    Site Not Available

  • Driscoll Children's Hospital

    Corpus Christi 4683416, Texas 4736286 78411
    United States

    Site Not Available

  • Medical City Dallas Hospital

    Dallas 4684888, Texas 4736286 75230
    United States

    Active - Recruiting

  • UT Southwestern/Simmons Cancer Center-Dallas

    Dallas 4684888, Texas 4736286 75390
    United States

    Site Not Available

  • El Paso Children's Hospital

    El Paso 5520993, Texas 4736286 79905
    United States

    Site Not Available

  • Cook Children's Medical Center

    Fort Worth 4691930, Texas 4736286 76104
    United States

    Site Not Available

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston 4699066, Texas 4736286 77030
    United States

    Site Not Available

  • Covenant Children's Hospital

    Lubbock 5525577, Texas 4736286 79410
    United States

    Active - Recruiting

  • UMC Cancer Center / UMC Health System

    Lubbock 5525577, Texas 4736286 79415
    United States

    Site Not Available

  • Children's Hospital of San Antonio

    San Antonio 4726206, Texas 4736286 78207
    United States

    Active - Recruiting

  • Methodist Children's Hospital of South Texas

    San Antonio 4726206, Texas 4736286 78229
    United States

    Site Not Available

  • University of Texas Health Science Center at San Antonio

    San Antonio 4726206, Texas 4736286 78229
    United States

    Active - Recruiting

  • Primary Children's Hospital

    Salt Lake City, Utah 84113
    United States

    Active - Recruiting

  • Primary Children's Hospital

    Salt Lake City 5780993, Utah 5549030 84113
    United States

    Site Not Available

  • University of Vermont and State Agricultural College

    Burlington, Vermont 05405
    United States

    Active - Recruiting

  • University of Vermont and State Agricultural College

    Burlington 5234372, Vermont 5242283 05405
    United States

    Site Not Available

  • University of Virginia Cancer Center

    Charlottesville, Virginia 22908
    United States

    Active - Recruiting

  • Inova Fairfax Hospital

    Falls Church, Virginia 22042
    United States

    Active - Recruiting

  • Children's Hospital of The King's Daughters

    Norfolk, Virginia 23507
    United States

    Active - Recruiting

  • VCU Massey Comprehensive Cancer Center

    Richmond, Virginia 23298
    United States

    Active - Recruiting

  • Virginia Commonwealth University/Massey Cancer Center

    Richmond, Virginia 23298
    United States

    Active - Recruiting

  • Carilion Children's

    Roanoke, Virginia 24014
    United States

    Active - Recruiting

  • University of Virginia Cancer Center

    Charlottesville 4752031, Virginia 6254928 22908
    United States

    Site Not Available

  • Inova Fairfax Hospital

    Falls Church 4758390, Virginia 6254928 22042
    United States

    Site Not Available

  • Children's Hospital of The King's Daughters

    Norfolk 4776222, Virginia 6254928 23507
    United States

    Site Not Available

  • VCU Massey Comprehensive Cancer Center

    Richmond 4781708, Virginia 6254928 23298
    United States

    Site Not Available

  • Carilion Children's

    Roanoke 4782167, Virginia 6254928 24014
    United States

    Site Not Available

  • Seattle Children's Hospital

    Seattle, Washington 98105
    United States

    Active - Recruiting

  • Providence Sacred Heart Medical Center and Children's Hospital

    Spokane, Washington 99204
    United States

    Active - Recruiting

  • Mary Bridge Children's Hospital and Health Center

    Tacoma, Washington 98405
    United States

    Active - Recruiting

  • Seattle Children's Hospital

    Seattle 5809844, Washington 5815135 98105
    United States

    Site Not Available

  • Providence Sacred Heart Medical Center and Children's Hospital

    Spokane 5811696, Washington 5815135 99204
    United States

    Site Not Available

  • Mary Bridge Children's Hospital and Health Center

    Tacoma 5812944, Washington 5815135 98405
    United States

    Site Not Available

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin 54301
    United States

    Active - Recruiting

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin 53792
    United States

    Active - Recruiting

  • Children's Hospital of Wisconsin

    Milwaukee, Wisconsin 53226
    United States

    Active - Recruiting

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay 5254962, Wisconsin 5279468 54301
    United States

    Site Not Available

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison 5261457, Wisconsin 5279468 53792
    United States

    Site Not Available

  • Children's Hospital of Wisconsin

    Milwaukee 5263045, Wisconsin 5279468 53226
    United States

    Site Not Available

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