EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

Last updated: September 20, 2024
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Overall Status: Active - Recruiting

Phase

N/A

Condition

Genitourinary Cancer

Breast Cancer

Cancer

Treatment

Control Arm ACSM Guidelines

Experimental Arm 6-12-25 repetitions per set

Exercise Regimen

Clinical Study ID

NCT06115486
EXERT-BCH
  • Ages 20-89
  • Female

Study Summary

The purpose of this research study is to evaluate the outcomes of two standard of care group exercise regimens to increase muscle mass in women who have been treated with breast cancer.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Age 20-89 years

  • Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasivecarcinoma of the breast

  • Women must have undergone treatment for breast cancer, including one or more of thefollowing: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonaltherapy. Women undergoing active chemotherapy are not allowed on study.Immunotherapy or targeted agent usage is allowed.

Exclusion

Exclusion Criteria:

  • Any current treatment with cytotoxic chemotherapy for breast cancer

  • Inability to safely engage in group sessions of resistance training as deemed bystudy PI

  • Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by PIto be unsafe to engage in resistance training

Study Design

Total Participants: 30
Treatment Group(s): 3
Primary Treatment: Control Arm ACSM Guidelines
Phase:
Study Start date:
January 09, 2024
Estimated Completion Date:
January 31, 2027

Study Description

This protocol seeks to analyze patient outcomes of two standard of care, time-efficient, monitored group exercise regimens of high-load resistance training to improve hypertrophy in women who have been treated for ductal carcinoma in situ or invasive carcinoma of the breast.

As part of the standard exercise program, patients will undergo a fitness evaluation at the AHNCI Exercise Oncology and Resiliency Center before the start of the exercise program. This evaluation will be used to customize the patient exercise program. The exercise program consists of small group training sessions held approximately 3 times per week at the center for 12 weeks (3 months). The fitness evaluation and exercise program are standard of care. Participation in this study will last the duration of the exercise program, about 3 months. All group exercise sessions will be closely monitored by the center staff who are Certified Strength and Conditioning Specialists (CSCS).

Connect with a study center

  • Allegheny General Hospital

    Pittsburgh, Pennsylvania 15212
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.