Evaluation of Meniscal Extrusion by Dynamic Ultrasonography in Patients With Ostearthritis

Last updated: March 4, 2025
Sponsor: Istituto Ortopedico Rizzoli
Overall Status: Completed

Phase

N/A

Condition

Knee Injuries

Osteoarthritis

Treatment

Ultrasonographic evaluation

Clinical Study ID

NCT06113536
US-MEN
  • Ages 18-80
  • All Genders

Study Summary

This is a diagnostic, open-label, single-center interventional study. The aim of the study is to evaluate the relationship between medial and lateral meniscus extrusion determined by dynamic ultrasound study and bone edema assessed by MRI study in patients with knee OA.

As a secondary objective, the correlation of the above parameters with the patient's symptomatology assessed by subject clinical questionnaires will be evaluated.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age between 18 and 80 years;

  2. Signs and symptoms of degenerative pathology of knee cartilage;

  3. Patients with Radiographic (X-ray or MRI) signs of OA (K-L grade 0-4); 3.

  4. Cooperative patients with pain that does not prevent orthostatism

  5. Ability and consent of patients to actively participate in clinical follow-up;

  6. Recently performed MRI (maximum 1 month).

Exclusion

Exclusion Criteria:

  1. Patients unable to express consent;

  2. Patients undergoing intra-articular infiltration of other substance in the previous 6 months;

  3. Patients undergoing knee surgery in the previous 12 months;

  4. Patients with malignant neoplasms;

  5. Patients with rheumatic diseases;

  6. Patients with a history of total/subtotal meniscectomy;

  7. Patients with symptomatology such that a dynamic examination in orthostatism is notpossible; 7.

  8. Patients abusing alcoholic beverages, drugs or medications;

  9. Body Mass Index > 40;

  10. Pregnant or lactating women;

  11. Patients with axis deviation > 5°.

Study Design

Total Participants: 202
Treatment Group(s): 1
Primary Treatment: Ultrasonographic evaluation
Phase:
Study Start date:
March 23, 2021
Estimated Completion Date:
January 21, 2025

Study Description

Patients with a diagnosis of knee OA will be included in a study involving evaluation of the correlation between meniscal extrusion assessed by dynamic ultrasonography and bone edema assessed on MRI. A total of 202 patients will be included, who, after providing their signed informed consent to participate in the study, will undergo dynamic ultrasonography. After giving signed consent to participate in the study, the patient will undergo the following examinations::

  • ultrasound evaluation for assessment of possible meniscal extrusion;

  • At the same time as the ultrasound examination, subjective questionnaires will be administered to patients.Recent radiological examinations of the patients or from the patient's medical record will be collected during or before the diagnostic investigation.

Connect with a study center

  • Istituto Ortopedico Rizzoli

    Bologna, 40136
    Italy

    Site Not Available

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