A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Last updated: March 10, 2025
Sponsor: Affiliated Hospital of Jiaxing University
Overall Status: Completed

Phase

N/A

Condition

Circulation Disorders

Vascular Diseases

Dizzy/fainting Spells

Treatment

N/A

Clinical Study ID

NCT06112769
2023-KY-603
  • Ages > 60
  • All Genders

Study Summary

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • age over 60 years

  • American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ

  • Surgery with radial artery puncture

  • Propofol induction

Exclusion

Exclusion Criteria:

  • BMI≥30kg/m2

  • People with short necks;

  • Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure <65mmHg)

  • Previous poorly controlled hypertension

  • Cardiac insufficiency , EF value<50%

  • Upper limb deep vein thrombosis

  • History of radiotherapy or neck surgery

  • Inability to maintain a supine position for necessary measurements

  • Mechanical ventilation status or inability to take deep breaths patients

  • gastrointestinal surgery

  • patients allergic to propofol.

Study Design

Total Participants: 64
Study Start date:
October 29, 2023
Estimated Completion Date:
January 31, 2024

Study Description

  1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV

  2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.

  3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Connect with a study center

  • Affiliated Hospital of Jiaxing University

    Jiaxing, Zhejiang 314000
    China

    Site Not Available

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