Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability

Last updated: July 7, 2025
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Overall Status: Active - Recruiting

Phase

N/A

Condition

Myocardial Ischemia

Coronary Artery Disease

Chest Pain

Treatment

training strategy with adaptation of training strategies to the ANS

training strategy (standard practice)

Clinical Study ID

NCT06107452
23CH152
2023-A01452-43
  • Ages > 18
  • All Genders

Study Summary

Cardiac readaptation aims to mitigate cardiovascular risks and enhance the quality of life among coronary patients. Our research laboratory has an international expertise in training optimization in top-athletes and a previous study has demonstrated the efficacy of optimizing cardiac rehabilitation through the power-force-velocity profile (PFVP). The findings exhibited significant improvements in aerobic capacity, muscular strength, and cardiovascular parameters among patients who were trained based on their PFVP. Guided training utilizing heart rate variability (HRV) is also garnering increasing interest as a means to optimize training load and promote recovery

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • >18

  • Acute Coronary Syndrome treated in the last 6 months

  • Medical revascularization (angioplasty ± stenting) or surgical (coronary arterybypass)

  • Initial CPETt: MPA ≥ 60w in women and ≥80w in men

  • French

  • Informed consent

Exclusion

Exclusion Criteria:

  • Significant co-morbidities limited practice of physical activity

Study Design

Total Participants: 110
Treatment Group(s): 2
Primary Treatment: training strategy with adaptation of training strategies to the ANS
Phase:
Study Start date:
February 05, 2024
Estimated Completion Date:
May 31, 2026

Study Description

Our study aims to evaluate the application of HRV in regulating training load based on fatigue levels in cardiac rehabilitation patients utilizing the PFVP framework.

Connect with a study center

  • Chu Saint-Etienne

    Saint-Étienne,
    France

    Active - Recruiting

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