Phase
Condition
Mild Cognitive Impairment
Mental Disability
Alzheimer's Disease
Treatment
N/AClinical Study ID
Ages 55-80 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Adults diagnosed with or suspected to have MCI (for MCI group) or are cognitivelynormal (for Control group)
Absence of other risk factors that might affect CAP (Central Auditory Processing)performance (e.g., active ear infections, congenital developmental delay, severehearing loss)
Age 55-80
Normal hearing sensitivity (<40 dB HL Pure Tone Average (average of 500, 1000, 2000Hz) thresholds bilaterally
Normal middle ear function defined by tympanometry (0.3-2.0 ml)
Native English speaker
Exclusion
Exclusion Criteria:
Active ear infections or abnormal middle ear pathology
Other health condition prohibiting the completion of the CAP test battery
Mild to profound peripheral hearing loss (>40 dB (decibel) HL (hearing loss) PureTone Average (average of 500, 1000, 2000 Hz) bilaterally
Adults unable to consent
Individuals who are not yet adults (infants, children, teenagers)
Prisoners
History of CNS (Central Nervous System) disorder that might severely impactcognitive function (e.g., Alzheimer's disease, Parkinson's disease, multiplesclerosis, neurosyphilis, intracranial tumors, history of significant head traumawith loss of consciousness (≥30 min), and cerebrovascular disease)
Severe mental illness (e.g., schizophrenia, bipolar disorder)
Current, uncontrolled medical condition that could affect cognition (e.g.,hypertension)
History of substance use disorder within the (other than nicotine/caffeine)
Non-correctable severe hearing or vision loss
Use of "Cognition Enhancing Drugs"
Frequent, severe headaches (occasional headaches or migraines are fine)
Study Design
Connect with a study center
Space Medicine Lab at Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire 03756
United StatesActive - Recruiting
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