Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial

Inclusion Criteria:

• Age between 35-65 years old, male or female;

• Grade 1 essential hypertension;

• Taking no antihypertensive drugs or taking antihypertensive drugs irregularly in thepast ;

• Sign the informed consent;

Exclusion Criteria:

• Significant liver and kidney dysfunction, ALT and AST upper the twice of normalrange, Scr≥2.0mg/dl, eGFR<60ml/(min·1. 73m2);

• Gastrointestinal diseases, which may affect drug absorption;

• Be allergic to the clinical trial medicine;

• Pregnant or breastfeeding women, men who plan to give birth within half a year;

• Combined with other serious primary diseases or malignant tumors;

• Hyperlipidemia with or without taking lipid-lowering drugs;

• Combined with left ventricular hypertrophy, ABI < 0.9, CIMT ≥ 0.9mm oratherosclerotic plaque;

• Hypertensive comorbidities (cerebrovascular disease, other cardiovascular diseases,renal disease, peripheral artery disease, retinopathy, diabetes);

• Other serious conditions in which is not fit for the study.