Prediction of Hypotension During Induction of General Anesthesia

Last updated: August 2, 2024
Sponsor: Ain Shams University
Overall Status: Active - Enrolling

Phase

N/A

Condition

Vascular Diseases

Dizzy/fainting Spells

Circulation Disorders

Treatment

Propfol - Fentanyl- Atracurium

Propofol - Fentanyl- Atracurium

Clinical Study ID

NCT06078228
FMASU MD205/2023
  • Ages 18-65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 1- Patients of American Society of Anesthesiologists (ASA) physical status I to IIof both genders.

2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI lessthan 40.

Exclusion

Exclusion Criteria:

  • Patients with

  1. Renal diseases.

  2. Hepatic diseases.

  3. ASA scores of 3-4.

  4. The presence of a left ventricular ejection fraction less than 50%.

  5. Age under 18 years old.

  6. Patient refusal.

  7. Coronary heart disease.

  8. Cardiac disease including cardiomyopathy and mild to severe valve disease.

  9. Pulmonary hypertension.

  10. Peripheral arterial disease.

  11. Preoperative cervical vascular ultrasound abnormalities including plaque,stenosis and anatomical variation.

  12. Any previous neck surgery or trauma.

Study Design

Total Participants: 70
Treatment Group(s): 2
Primary Treatment: Propfol - Fentanyl- Atracurium
Phase:
Study Start date:
September 24, 2023
Estimated Completion Date:
August 17, 2024

Study Description

  • Type of Study: Observational Prospective Cohort Design.

  • Study Setting and ethical consideration: The approval of the Scientific Research Ethics Committee of the Faculty of Medicine, Ain Shams University will be obtained before starting work on the study. This study will be conducted in operating theatres of Ain Shams University Hospitals. Informed written consents to participate will be obtained from the patients.

  • Study Period: One year (October 2023-October 2024)

  • Study Population: Adult patient undergoing elective surgeries.

Connect with a study center

  • Ain Shams University

    Cairo, Abbassia 7154411
    Egypt

    Site Not Available

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