TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

Phase

N/A

Condition

Alcohol Use Disorder

Addictions

Alcohol Dependence

Treatment

Online Mutual Support Groups

Mindfulness-based relapse prevention

Clinical Study ID

NCT06074341

2212028742

R01AA031159

Ages > 18
All Genders
Accepts Healthy Volunteers

Study Summary

This project will evaluate the effectiveness and mechanisms of mindfulness-based relapse prevention (MBRP) delivered via video conferencing, as compared to referral to online mutual support groups, in supporting long-term whole-person recovery and improvements in neurobiologically-informed domains of addiction among individuals with alcohol use disorder who are interested in reducing or stopping drinking. The project will also examine the reach, effectiveness, adoption, implementation, and maintenance of MBRP as an accessible and freely available continuing care option that supports long-term recovery from alcohol use disorder in all communities nationwide, including medically underserved and health professional shortage areas.

Eligibility Criteria

Inclusion

Inclusion Criteria:

At least 18 years old
Received AUD treatment or made a self-change attempt to reduce or stop drinking inthe past 3 months or is interested in reducing or stopping drinking
Meet criteria for a current AUD
Engaged in heavy drinking (more than 14 standard drinks per week or more than 4drinks on a single day for men and more than 7 drinks per week or more than 3 drinkson a single day for women) in the past 6-months
Able to understand all study procedures and able to consent in English or Spanish.
Be willing to use a personal smart phone or tablet that is connected to theinternet, or being willing to use a study-provided tablet
Have access to a valid U.S. mailing address for receiving dried blood spot card orblood collection device.

Exclusion

Exclusion Criteria:

Current symptoms of psychosis or mania.
Have a substance use disorder requiring a higher level of care than outpatienttreatment (e.g., severe alcohol use disorder requiring inpatient detoxification).

Study Design

Online Mutual Support Groups

September 13, 2023

July 31, 2028

Study Description

The goal of this study is to examine the effectiveness of mindfulness-based relapse prevention (MBRP) groups delivered via Zoom in promoting whole-person recovery from alcohol use disorder, and to examine how MBRP affects mechanisms of behavior change based on neurobiologically-informed addiction cycle domains. The investigators will use a hybrid effectiveness-implementation design to prospectively test the effectiveness of MBRP, as well as identify barriers and facilitators of MBRP group participation to inform future implementation of MBRP continuing care. Individuals (n=430) who have recently engaged in a change attempt to stop or reduce their drinking (via treatment or self-change) will be randomized to either MBRP groups via Zoom or referral to online mutual support. Participants will complete measures of psychosocial functioning, alcohol and other drug use, addiction cycle domains, and previously established predictors of recovery every 6 months for 3 years. Using a mixed methods design in the MBRP group, the investigators will examine facilitators and barriers to participation and engagement in MBRP, and assess the reach, effectiveness, adoption, implementation, and maintenance of MBRP via Zoom as continuing care in communities nationwide.

Connect with a study center

University of New Mexico
Albuquerque, New Mexico 87131
United States
Site Not Available

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