Registry of the Patient Experience for Carpal Tunnel Release

Inclusion Criteria 1. ≥18 years of age 2. Clinical diagnosis of unilateral or bilateral CTS 3. A clinical decision has been made to perform CTR on one or both hands 4. CTS-6 score ≥12 in the target hand(s)* 5. Confirmatory diagnostic testing in the target hand(s)*:

1. CTR-US: Confirmatory diagnostic testing with ultrasound (median nervecross-sectional area ≥10 mm2 in the proximal carpal tunnel region)

2. ECTR or OCTR: Confirmatory electrodiagnostic testing 6. Prior failure of one or morenonsurgical treatment options (e.g., physical activity modification, bracing,splinting, corticosteroid injection) in the target hand(s) 7. Patient agrees tocomplete follow-up questionnaires over a 24-month period 8. Patient has a validsmart phone number and/or email address to receive and answer follow-upquestionnaires

Note: An asterisk (*) denotes that this criterion must be applied to the target hand for unilateral CTR procedures, or to both hands for simultaneous bilateral CTR procedures.

Exclusion Criteria:

1. Patient meets any of the contraindications per Instruction For Use (IFU)

2. Patient has other medical, social, or psychological conditions that, in the opinionof the investigator, preclude them from completing all registry requirements.