Multimodal Computed Tomography in Patients With Acute Hemorrhagic Stroke

Last updated: April 2, 2025
Sponsor: Xiaolin Chen, MD
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hemorrhage

Stroke

Blood Clots

Treatment

Multimodal CT

Clinical Study ID

NCT06061185
KY 2024-007-02
  • Ages 18-85
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Acute hemorrhagic stroke is a series of neurosurgical diseases characterized by bleeding with high morbidity and mortality. It accounts for about 20% of all strokes worldwide and mainly includes subtypes such as intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Multimodal computed tomography including non-contrast computed tomography, computed tomography angiography and computed tomography perfusion, is of great important in understanding pathophysiological changes, evaluating prognosis and guiding interventions in these diseases.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. age ≥ 18, ≤ 85 years;

  2. presence with hemorrhagic stroke

Exclusion

Exclusion Criteria:

  1. with a history of previous history of ischemic/hemorrhagic stroke;

  2. admission to the emergency department more than a week after symptom onset;

  3. serious medical history or existing comorbidities;

  4. physical disability due to previous diseases;

  5. prior treatment such as external ventricular drainage, digital subtractionangiography and lumbar puncture in other institution;

  6. poor original image quality;

  7. incomplete follow-up.

Study Design

Total Participants: 10000
Treatment Group(s): 1
Primary Treatment: Multimodal CT
Phase:
Study Start date:
January 01, 2020
Estimated Completion Date:
April 01, 2032

Study Description

Study overview: The data of the population in the MACTAHS study will be prospectively collected. The CT strategies for acute hemorrhagic stroke are mainly three categories: non-contrast computed tomography, computed tomography angiography and computed tomography perfusion. Each participants will be followed at least until 1 year after discharge. Finally, investigators will clarify the prognostic value of multimodal CT for patients with acute hemorrhagic stroke.

Sample size: About 10000 patients will be enrolled in this study. All the population will be expected to undergo non-contrast computed tomography, computed tomography angiography and computed tomography perfusion.

Study endpoints: Neurological functional outcomes, delayed ischemia and infarction, recurrent bleeding, cognition and emotional dysfunction, systemic in-hospital systemic complications, rehabilitation and recovery status will be evaluated and follow-up would be completed.

Connect with a study center

  • Beijing Tiantan Hospital

    Beijing, Beijing 100070
    China

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.