Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients

Inclusion Criteria:

• Patients ≥ 18 years old
• Malnourished patients according to GLIM criteria
• Patients with a high energy requirement (1.5kcal/ml) requiring the intake of 2bottles of ONS per day for at least 12 weeks
• Patients presenting any of the following clinical situations:
• Elderly patients requiring oral nutritional support
• Patients with digestive pathology including but not restricted to inflammatory boweldisease, short bowel syndrome, pancreatitis, without active malabsorption andmaldigestion.
• Chronic diseases such as COPD, mild to moderate renal disease, HIV
• Oncologic patients with Eastern Cooperative Oncology Group (ECOG) 0-1
• Patients who have given their consent to participate
• Patients who, in the opinion of the physician, have the capacity to answer thestudy questionnaires themselves or their caregivers

Exclusion Criteria:

• Patients who need ONS due to surgical or acute illness*
• Patients with known intolerance or allergy to cow's milk, soya or peas
• Patients with hyperthyroidism. Patients with uncontrolled hypothyroidism
• Uncontrolled diabetic patients (HbA1c >8%)
• Patients requiring enteral nutrition by tube or ostomy
• Patients with moderate and serious renal insufficiency < 30ml/min/1,73 m2
• Patients who have value creatinine:
• 1,70 mg/dl - 150,31umol/L Men
• 1,50 mg/dl - 132,63umol/L Women
• Patients with levels of haemoglobin <10 g/dl, transferrin <150 mg /dl