Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex

Key Inclusion Criteria:

• Be willing to sign the informed consent and deemed capable of complying with therequirements of the study protocol
• Meets all of the following criteria in at least one eye: have more than 10 lashes withcollarettes present on the upper lid; have the presence of one or more mites with lashepilation of the upper and lower lids; have evidence of meibomian gland dysfunction;have at least mild erythema of the lower lid; have a tear breakup time of less than 10seconds; and have intact partial to full meibomian glands in at least 33% of the totalmeibomian gland area of the lower lid

Key Exclusion Criteria:

• Have used lid hygiene products within 7 days of Day 1 or unwilling to forego the useof lid hygiene products during the study
• Have used systemic antihistamines within 30 days of Day 1
• Have used artificial eyelashes, eyelash extensions, or had other cosmetic eyelash oreyelid procedures within 7 days of Day 1 or be unwilling to forego their use duringthe study
• Contact lens wear within 7 days of Day 1 or unwilling to forego contact lens wear forthe duration of the study
• Be pregnant or lactating at Day 1