Comparison of the Efficiency of ESWT and Ozone Injection in Patients With Chronic Plantar Fasciitis

Last updated: September 11, 2023
Sponsor: Ankara City Hospital Bilkent
Overall Status: Active - Recruiting

Phase

N/A

Condition

Soft Tissue Infections

Treatment

Ozone Generator

Extracorporeal shock wave therapy device

Clinical Study ID

NCT06041230
E2-23-3838
  • Ages 18-65
  • All Genders

Study Summary

Extracorporeal Shock Wave Therapy (ESWT) is a conservative treatment method that has been widely used in musculoskeletal diseases in recent years. Its mechanism is to provide hyperstimulation and vascularity increase with the help of acoustic waves focused on a specific area, thus accelerating healing and reducing pain. This method, which is frequently used in plantar fasciitis, is frequently applied to patients whose symptoms persist despite first-line treatment strategies.

Ozone injections have been frequently used in musculoskeletal disorders in recent years and are mainly used in osteoarthritis, osteomyelitis, tendon, fascia and ligament injuries, vertebra and disc pathologies and neuropathic pain. Analgesic effect on musculoskeletal system (release of endorphins, activation of antinociceptive system, reduction of edema) anti-inflammatory effect (regulation of cytokine release, reduction of superoxide radicals, modulation of prostaglandin), regulation of local oxygenation and circulation, tissue repair (neutralization of preteolytic enzymes, fibroblast proliferation) and has an antimicrobial effect. Although it is also used in the treatment of plantar fasciitis, there are limited articles on this subject in the literature.

In our study, it was aimed to compare the effectiveness of ESWT and ozone injection therapy, which are two treatment strategies with regenerative action mechanisms, in patients with resistant plantar fasciitis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Be over 18 years old
  • Heel pain lasting longer than 3 months
  • Localized pain and tenderness on palpation on the medial aspect of the calcanealtuberosity when the ankle is fully dorsiflexed.
  • In the first step of walking, >50 mm according to VAS. and description of pain
  • Presence of plantar fasciitis typical findings on ultrasonography (thickening morethan 4 mm in the proximal plantar fascia with changes in fibril pattern)
  • Failure to respond to conservative treatment before (nonsteroidal anti-inflammatorydrugs, stretching, heel cushion, shoe modifications, orthotics, cold, heat, taping,massage)

Exclusion

Exclusion Criteria:

  • being under the age of 18
  • Any skin lesions in the heel area
  • Inflammatory, rheumatic arthritis
  • Having a history of fracture, trauma or operation in the heel area
  • Systemic infection or malignancy
  • Having a pacemaker
  • Local injection to the heel area in the last 6 months or use of topical or oralnonsteroidal anti-inflammatory drugs in the last 2 weeks

Study Design

Total Participants: 48
Treatment Group(s): 2
Primary Treatment: Ozone Generator
Phase:
Study Start date:
July 12, 2023
Estimated Completion Date:
November 15, 2023

Connect with a study center

  • Ankara Bilkent City Hospital

    Ankara, 06100
    Turkey

    Active - Recruiting

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