Prevalence of Anemia and Growth Assessment in Acute Gastroenteritis

Last updated: October 31, 2024
Sponsor: Assiut University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Gastroenteritis

Treatment

N/A

Clinical Study ID

NCT06038305
anemia and growth in AGE
  • Ages 1-2
  • All Genders

Study Summary

  1. Assessment of the growth parameters in infants admitted with acute gastroenteritis.

  2. Determine the prevalence of anemia in infants admitted with acute gastroenteritis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Infants with acute gastroenteritis.

  • Infants aged from 1 month and up to 2 years.

Exclusion

Exclusion Criteria:

  • Infants aged less than 1 month and more than 2 years.

  • Infants with persistent and chronic diarrhea.

  • Infants with acute gastroenteritis in association with chronic disease

Study Design

Total Participants: 297
Study Start date:
January 01, 2024
Estimated Completion Date:
February 28, 2025

Study Description

Gastroenteritis is inflammation of the stomach, small intestine, or large intestine, leading to a combination of abdominal pain, cramping, nausea, vomiting, and diarrhea. Acute gastroenteritis usually lasts fewer than 14 days. Worldwide, gastroenteritis affects 3 to 5 billion children each year. Up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections. Malnutrition, immunosuppression, young age, and an increase in the preceding diarrhea burdens are risk factors for the development of persistent diarrhea. A substantial proportion of global malnutrition is due to impaired intestinal absorptive function resulting from multiple and repeated enteric infections. These include recurrent acute infections as well as persistent infections, even those without overt liquid diarrhea.

Child growth is internationally recognized as the best global indicator of physical well-being in children because poor feeding practices-both in quantity and quality-and infections, or more often a combination of the two, are major factors that affect physical growth and mental development in children. The most important measurements needed for growth assessment are recumbent length or height, weight and head circumference. These fundamental anthropometric measures should be obtained and interpreted at each well child visit, and are typically sufficient for growth assessment.

In this study, the prevalence of anemia and growth of infants admitted with acute gastroenteritis at Assiut University Children Hospital will be assessed. Anemia is a global public health problem, with important consequences for human health and the social and economic development of each nation. It results from single or multiple causes that act simultaneously, influencing children's health, their cognitive and physical development, and immunity, increasing the risk of infections and infant mortality.

Connect with a study center

  • Assiut University

    Assiut, 71515
    Egypt

    Active - Recruiting

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