Timing of Endoscopy in Cirrhotic Patients with Acute Variceal Bleeding

Inclusion Criteria:

1. patients with AUGIB which is highly suspected to be caused by gastroesophagealvariceal rupture;

2. patients with a diagnosis of liver cirrhosis based on imaging and pathology;

3. patients and/or their relatives who sign informed consents;

4. patients' age ≥18 years.

Exclusion Criteria:

1. patients who have undergone endoscopy at other hospitals before admissions;

2. patients' hemodynamics are unstable after resuscitation;

3. patients with severe cardiovascular or cerebrovascular diseases or renal injury;

4. patients who have taken anticoagulants or antiplatelet drugs within 2 weeks beforeadmissions, or are diagnosed with severe hematological diseases;

5. patients with human immunodeficiency virus or other acquired or congenital immunedeficiency diseases;

6. patients with mental illness;

7. pregnancy.