Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars

Last updated: July 27, 2024
Sponsor: Alexandria University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Scar Tissue

Skin Wounds

Treatment

Microneedling with topical application of regular insulin

Microneedling with topical application of saline

Clinical Study ID

NCT06021275
Scar 1
  • Ages 12-60
  • All Genders

Study Summary

Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients aged 12 to 60 years

  2. Atrophic scars (traumatic or surgical)

  3. Completely healed scars

Exclusion

Exclusion Criteria:

  1. Patients with a tendency or history of hypertrophic or keloidal scars

  2. Patients who received treatment for their scar in the past 3 months

  3. Diabetic patients or those with a history of Dysglycemia

  4. Pregnant, or lactating females

  5. Patients with active infection at the site of scar

  6. Patients currently receiving isotretinoin treatment or in the past month

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Microneedling with topical application of regular insulin
Phase:
Study Start date:
October 01, 2023
Estimated Completion Date:
December 31, 2024

Connect with a study center

  • Alexandria University, Faculty of Medicine

    Alexandria,
    Egypt

    Active - Recruiting

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