A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

Last updated: August 21, 2023
Sponsor: Tongji Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Thrombosis

Dysfunctional Uterine Bleeding

Fever

Treatment

N/A

Clinical Study ID

NCT06011902
RESORT
  • All Genders

Study Summary

This is a multi-center, retrospective clinical study to analyze the clinical features, laboratory indicators, imaging changes, treatment options and long-term prognosis in patients with sever fever with thrombocytopenia syndrome. All hospitalized patients with sever fever with thrombocytopenia diagnosed between 2016 and 2022 were included from the electronic medical record system of 8 centers, and demographics, hospitalization information, clinical information, laboratory or imaging examinations, treatment options, and outcomes were collected.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age and gender are not limited;
  • Hospitalized patients diagnosed with severe fever with thrombocytopenia syndrome haveat least one of the following laboratory test results: serum severe fever withthrombocytopenia syndrome bunyavirus (SFTSV)-specific IgM antibody positive or IgGantibody level increased more than 4 times; or positive for SFTSV RNA; or positive forSFTSV nucleic acid detected by real-time fluorescent quantitative RT-PCR; or SFTSVisolated from case specimens.

Exclusion

Exclusion Criteria:

  • Patients who were found to be positive for other tick-borne pathogens by PCR analysisof blood samples in the acute phase;
  • It is difficult to conduct outpatient follow-up due to mental disorders, dementia,combined diseases such as osteoarthropathy, stroke, pulmonary embolism, etc. that leadto inability to move freely;
  • No outpatient follow-up visit after discharge, and repeated confirmation by phone callstill unable to get in touch;
  • Due to living in other places, nursing homes, welfare homes, unable to participate inoutpatient follow-up after making an appointment by phone;
  • Currently participating in clinical trials of other drugs or medical devices;
  • The researchers think it is not suitable for inclusion.

Study Design

Total Participants: 1500
Study Start date:
October 25, 2021
Estimated Completion Date:
March 31, 2024

Connect with a study center

  • NO.1 Peoples Hospital of Guangshui

    Guangshui, Hubei
    China

    Active - Recruiting

  • Huanggang Central Hospital

    Huanggang, Hubei
    China

    Active - Recruiting

  • People's Hospital Of Luotian County

    Huanggang, Hubei
    China

    Active - Recruiting

  • People's Hospital of Macheng city Affiliated Hospital of Hubei Univerciy of science and technology

    Macheng, Hubei
    China

    Active - Recruiting

  • Suizhou Central Hospital

    Suizhou, Hubei
    China

    Active - Recruiting

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei 430030
    China

    Active - Recruiting

  • Xianning Central Hospital

    Xianning, Hubei
    China

    Active - Recruiting

  • Yichang Third Peoples Hospital

    Yichang, Hubei
    China

    Active - Recruiting

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