Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

Inclusion Criteria:

• Age over 18 years

• Written informed consent

• Diagnosis of recurrent or isolated depressive episode according to DSM IV criteria (A.P.A. 1994).

• Stable antidepressant treatment for 3 weeks

• MADRS score ≥ 20

• SSI score > 3

• Subject affiliated to a health insurance system

• Woman with effective contraception and agreeing to maintain it throughout the studyperiod.

Exclusion Criteria:

• Depression with psychotic features Axis I (DSM IV) co-morbid diagnosis ofschizophrenia, alcohol and/or other substance dependence (or abuse) (lifetime)

• Patient who has already undergone an electroconvulsive therapy course for thecurrent episode and does not respond to this treatment

• Patient deprived of liberty

• Patient with high suicide risk (item 10 MADRS > 4) in the absence of hospitalization

• Contraindication to tDCS: intracerebral metallic implant (with the exception ofdental implants), cardiac pacemaker, active or non-implanted devices in the regionof the head, acute eczema in the planned stimulation area

• Pregnant, parturient or breastfeeding woman

• Simultaneous participation in another interventional research