Phase
Condition
N/ATreatment
Transcranial direct current stimulation (tDCS) (active)
Transcranial direct current stimulation (tDCS) (Sham)
Clinical Study ID
Ages > 65 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Aged 65 and above.
Ability to speak and read English.
Ability to walk independently and continuously for at least 1 minute.
Elevated gait variability as defined by a coefficient of variation (CoV) aboutaverage stride time larger and equal to 0.025 during straight-line walking atpreferred speed.
Exclusion
Exclusion Criteria:
More than mild cognitive impairment defined by a Montreal Cognitive Assessment (MoCA) score less than 18.
Parkinson's disease, multiple sclerosis, stroke, active brain tumor, or otherneurological disorders.
Self-reported pain or lower extremity deformity that significantly disrupts walking.
Contraindications to MRI or tDCS.
An episode of acute illness or exacerbation of a diagnosis that requireshospitalization or active treatment within the past 3 months.
Current treatment for congestive heart failure, angina, uncontrolled arrythmia, deepvein thrombosis, or other uncontrolled cardiovascular events.
Myocardial infarction, coronary artery bypass grafting, angioplasty, or othercardiac conditions within the past 3 months,
Active cancer for which chemo/radiation therapy is being received.
Psychiatric co-morbidity including major depressive disorder, schizophrenia,psychosis, or other psychiatric illness.
Recent use of any sedating medications (sedatives, anti-psychotics, hypnotics,anti-depressants) or change in medication within the previous month.
Chronic vertigo or other diagnosed vestibular disorders.
Legal blindness, visual impairments that cannot be corrected with glasses, contactlenses, medicine, or surgery.
Those without WiFi access
Those who do not plan to live in their current homes for the duration of the study
Study Design
Study Description
Connect with a study center
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife
Boston, Massachusetts 02131
United StatesActive - Recruiting

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