Increasing Physical Activity Through Personalised Motivational Messaging to Improve Cognitive Function in Lung Cancer Survivors

Last updated: August 15, 2023
Sponsor: The University of Hong Kong
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Lung Cancer

Neoplasms

Mild Cognitive Impairment

Treatment

Chat-type support message delivery

Regular message delivery

Clinical Study ID

NCT06003335
uhongkongc9ttii37
  • Ages > 18
  • All Genders

Study Summary

Objectives: To examine the effectiveness of a personalised motivational messaging intervention for improving cognitive function in lung cancer survivors.

Hypothesis to be tested: Lung cancer survivors receiving personalised motivational messaging will have better cognitive function than usual care.

Design and subjects: A randomised controlled trial in 196 lung cancer survivors with cancer-related cognitive impairment.

Intervention: The intervention group will be equipped with a wearable activity tracker for 3 months and receive personalised motivational messages via instant messaging applications (e.g., WhatsApp) to promote physical exercise. The intervention will include 1) regular messages sent at preferred times and frequencies allowing participants to choose suggested physical activity goals, and 2) support via chat-type messaging such as goal setting, real-time counselling, and practical advice. The control group will receive a leaflet on cognitive impairment with reminder text messages for follow-up surveys.

Main outcome measures: Data will be conducted at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up). Primary outcome will be cognitive function measured by HK-MoCA (objective) and Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) scale (subjective). Secondary outcomes are physical activity (IPAQ-SF), self-efficacy for exercise (SEE), psychological well-being (PHQ-4), and quality of life (EORTC QLQ-C30).

Data analysis: Intention-to-treat, post-trial qualitative (compliance with the intervention), and cost-effectiveness analyses will be conducted. We will follow the CONSORT-EHEALTH checklist.

Expected results: This trial will provide evidence on the effectiveness of the proposed intervention on improving cognitive function and increasing physical activity among lung cancer survivors.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. aged ≥ 18 years;
  2. diagnosed with stage I-III non-metastatic NSCLC cancer;
  3. completed primary treatment with curative intent (surgery, chemotherapy and/orradiation therapy) 6 months to 5 years prior to the baseline assessment with norecurrence or occurrence of additional cancers;
  4. identified as having mild cognitive impairment by the HK-MoCA 5-Min Protocol (≤ 7thage- and education-corrected percentile cut-off score);
  5. not engaged in regular exercise (defined as < 150 min of moderate-intensity exerciseper week).

Exclusion

Exclusion Criteria:

  1. inadequate reading and verbal Cantonese comprehension for the study activities;
  2. diagnosed with dementia;
  3. unable to use mobile phone text messaging applications (e.g., WhatsApp).

Study Design

Total Participants: 120
Treatment Group(s): 2
Primary Treatment: Chat-type support message delivery
Phase:
Study Start date:
March 01, 2024
Estimated Completion Date:
April 30, 2025

Connect with a study center

  • School of Nursing, The University of Hong Kong

    Hong Kong,
    Hong Kong

    Site Not Available

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