Phase
Condition
Vomiting
Hearing Loss
Deafness
Treatment
YPS-201b
betahistine
Clinical Study ID
Ages 19-80 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patients with dizziness (Meniere's) only, who understand the nature of the study andare willing to participate voluntarily.
The frequency of the hearing loss is between 250 kHz and 1 kHz.
Patients with bilateral 500, 1000, and 2000 Hz hearing threshold averages within 65dB HL
Patients who have received conventional pharmacotherapy for other dizzinessconditions with a washout period of 2 months.
To be eligible for subjects in the active phase of the disease, there must be atleast 1 vertigo attack in the 6 months before study entry.
If tests for renal function, electrolytes, etc. are performed and no problems arefound
Exclusion
Exclusion Criteria:
Patients with an otologic condition other than Meniere'ss (dizziness) (otitis media,profound hearing loss, hyperacusis, etc.).
Patients' conditions that may affect EEG measurements, such as a stroke, brainhemorrhage, or brain tumor.
Patients with kidney disease
Patients Have or have had a serious medical condition, such as cancer (includingleukemia, blood cancers, epilepsy, and neuropsychiatric conditions).
Patients with an artificial implant in the body (cochlear implant, hip joint,pacemaker, etc.)
Women of childbearing potential, pregnant women, or nursing mothers
Patients who can have Injuries or dermatologic abnormalities at the site ofapplication of the equipment.
Patients with coronary artery disease, uncontrolled high blood pressure, or otherserious medical conditions (including kidney disease).
Study Design
Connect with a study center
Seoul National University Hospital
Seoul,
Korea, Republic ofActive - Recruiting
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