The Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

Last updated: August 3, 2023
Sponsor: Amway (China) R&D Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Skin Aging

Treatment

Placebo Drink

Amway Herbal Drink

Clinical Study ID

NCT05986799
23-RD-05-AY-001
  • Ages 30-60
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This goal of this two arms, randomized, double-blind controlled trial is to study whether Amway herbal drink could improve skin anti-aging in the middle-aged people of 30-60 years old. The main questions it aims to answer are:

  1. whether skin elasticity will be improved measured by Cutometer

  2. whether skin wrinkles/roughness/pores will be improved measured by Antera 3D

30 eligible Participants will be enrolled in one center and randomly assigned to two study groups (Amway herbal drink group and placebo drink group). Up to four study visits will be made by the subject over a 3-month period intervention and all clinical data will be captured and recorded into CTMS (Clinical Trial Management System) for data analysis and reporting.

Researchers will compare Amway herbal drink group and placebo drink group to see if consumption of Amway herbal drink could significantly improve skin anti-aging at the end of the study.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male and female subjects, aged 30 to 60 years, with a gender ratio of 3:7;
  • Subjects are healthy;
  • Visual assessment, smoothness is greater than or equal to 3 points (according to theTest Method of Efficacy Measurement of Nourishing Cosmetic Products issued by ChineseAssociation of Fragrance Flavor and Cosmetic Industries, the smaller the index, thebetter. Please refer to appendix II);
  • Visual assessment, the gloss index is greater than or equal to 4 points (according tothe Unilever Radiance Scale, the smaller the index is the better. Please refer toappendix III);
  • Subjects could not use facial whitening and moisturizing products during the trial;
  • Agree not to take other oral products with similar efficacy (such as collagen, sodiumhyaluronate, etc.) during the trial. During the trial, participants agreed not to takeany drugs or supplements. Do not do any medical beauty projects during the trial, donot participate in other interventional clinical research;
  • Have a full understanding of the purpose, benefits, and possible risks and sideeffects of the study;
  • Willing to comply with all research requirements and procedures;
  • Understand the test procedure, read, and sign an appropriate Informed Consent Formindicating their willingness to participate.

Exclusion

Exclusion Criteria:

  • Use of any medications or supplements that may alter skin properties during the first 3 months of enrollment;
  • Skin disease patients;
  • Ggastrointestinal symptoms being treated;
  • Lactose intolerance, allergy to fish and its products;
  • Present with other organic diseases that affect intestinal function, such as historyof gastrointestinal resection, colon or rectal cancer, inflammatory bowel disease,diabetes, hyperthyroidism or hypothyroidism, congenital megacolon, scleroderma,anorexia nervosa, etc.;
  • Controlling diet, exercising more, or taking medications to control weight or affectappetite in the last 3 months;
  • Subjects have any of the following medical history or clinical findings that mayaffect the evaluation of the trial effect: significant gastrointestinal disorders,liver, kidney, endocrine, hematological, respiratory and cardiovascular diseases;
  • Abuse of alcohol or other illicit drugs, supplements currently or in the past, or OTCprescription drugs that may cause intestinal dysfunction or interfere with theevaluation of trial effects;
  • Frequent use of drugs that may affect gastrointestinal function or the immune system,as judged by the researcher;
  • Use of laxatives or other digestive substances in the 2 weeks prior to trialcommencement;
  • Women who are pregnant or breastfeeding, or who plan to become pregnant during thetrial;
  • PI considers that volunteers cannot fully cooperate with the trial arrangement.

Study Design

Total Participants: 30
Treatment Group(s): 2
Primary Treatment: Placebo Drink
Phase:
Study Start date:
August 13, 2023
Estimated Completion Date:
November 30, 2023

Connect with a study center

  • Ai You Mei Medical Beauty Clinic

    Jinhua, Zhejiang
    China

    Active - Recruiting

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