Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation

Inclusion Criteria:

• Age≥18 years, regardless of sex;
• Patients with symptomatic or asymptomatic cerebral vascular stenosis (includinginternal carotid artery system and vertebrobasilar system) who are candidates forelective cerebrovascular stenting.
• Patients or their immediate family members are able and willing to sign informedconsent.

Exclusion Criteria:

• Patients with progressive stroke;
• mRS≥ 2 points before admission;
• Patients with other surgical treatments;
• Patients with other serious diseases or a life expectancy of less than 3 months
• Patients who had contraindication of remote ischemic conditioning, such as severe softtissue injury, fracture or vascular injury in the upper extremities, venous thrombosisin the acute or subacute stage of upper extremities;
• Laboratory test indicators are unqualified: aspartate aminotransferase or alanineaminotransferase is 3 times higher than the upper limit of the normal range, bloodcreatinine > 265umol/L (>3mg/dl), platelet < 100×109/L, international normalized ratio (INR), activated partial thromboplastin time (APTT), prothrombin time (PT) exceed theupper limit of the normal range;
• Pregnant or lactating women;
• Patients who are participating in other clinical studies, or who have participated inother clinical studies within 3 months prior to enrollment;
• Unwillingness to be followed up or poor adherence to treatment;
• Other circumstances that the investigator considers unsuitable for enrolment.