Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain

Inclusion Criteria:

• Patient 18 years or older;

• Pain refractory to conservative treatments for more than 2 months, non-surgicalpatients

• Cervicobrachialgia due to disc herniation

• Chronic discogenic pain (1 or 2 cervical discs) with concordant MRI;

• Patient agreeing to participate in the study and having given written consent;

• Patient enrolled in a health insurance plan.

Exclusion Criteria:

• Prior surgical treatment of the disc(s) studied;

• Sick leave of more than 12 months secondary to painful symptoms;

• Patient with Modic 1 score or more

• History of cognitive-behavioral disorders that could affect the completion ofself-questionnaires;

• Local or systemic infection, or suspicion of infection;

• Severe coagulation disorders;

• Other inflammatory rheumatic disease;

• Severe underlying pathology with life expectancy <1 year;

• Women of childbearing age who are pregnant at the inclusion visit or who wish tobecome pregnant before the administration of the treatment (V0);

• Known allergy to contrast material and/or local anesthetic substances;

• Patients who cannot read or write Italian;

• Major person benefiting from a legal protection regime (guardianship, curatorship,safeguard of justice);