RASECAL-Bronchoscopic Ambusampler

Inclusion Criteria:

(All are required)

• Clinicians experienced in performing bronchoscopies (i.e. bronchoscopists shouldhave performed a minimum 5 bronchoscopies in mechanically ventilated patients and aminimum of 5 bronchoscopies in a simulated or practice setting).

• Clinicians who have undergone the online product-training module for the use of theAmbu Bronchosampler, with self-certification documented.

• Clinicians who have simulated the online product training module using an AmbuBronchosampler and Ambu Ascope4 a minimum of 5 times in a practice setting and haveself-certified.

Population

• Patients ≥ 18 years old

• Patients on mechanical ventilation with Acute respiratory failure for >4h

• Patients eligible for a clinically indicated bronchoscopy with fluid sampling.Patient information has been explained and verbal or written consent has beenobtained

Exclusion Criteria:

Investigators

• Investigators who have not completed product training in aScope BronchoSampler byonline and hands-on from Ambu product specialists or an experienced user from thesite.

• Investigators with experience in < 5 self-verified simulated fluid samplingprocedures using the Ambu BronchoSampler 4.8.2 Population

• Clinician concern regarding safety of bronchoscopy

• Involved study personal not available to perform the procedure and enroll thepatient