Non-phonatory Exercises in Patients with Unilateral Vocal Fold Paralysis Post-thyroidectomy

Last updated: March 10, 2025
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Overall Status: Completed

Phase

N/A

Condition

Cataplexy

Treatment

Non-phonatory exercises

Clinical Study ID

NCT05963165
5559
  • Ages > 18
  • All Genders

Study Summary

Thyroidectomy is the most common iatrogenic cause of vocal fold paralysis. Patients complain of hoarseness caused by incomplete glottic closure and have effort to raise vocal intensity with consequent elevation of the larynx and/or involvement of supraglottic structures in phonation. These compensation mechanisms result in a shift of the fundamental frequency towards more serious tones or falsetto voice emissions.

The first choice treatment is speech therapy which aims to obtain better glottic closure, preventing ankylosis of the crico-arytenoid joint. In order to promote better glottic closure without risking the onset or increase of dysfunctional compensation, the idea behind this project is to propose non-phonatory adduction exercises in the first post-operative week.

The primary objective of the study is to compare patients who will perform non-phonatory exercises in parallel with medical therapy for one week and patients who will perform standard medical therapy only during the first week.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • vocal fold paralysis after thyrodectomy

  • ability to sign an informed consent

Exclusion

Exclusion Criteria:

  • Vocal fold paralysis with different etiology

  • Previous history of laryngeal, pulmonary or gastric surgery

  • History of vocal or laryngeal pathologies that have required therapy

  • Current or previous lung disorders

  • Hearing loss

  • Motor or neurological deficits

  • Presence of malignant diseases

  • Presence of speech or reading disorders

Study Design

Total Participants: 56
Treatment Group(s): 1
Primary Treatment: Non-phonatory exercises
Phase:
Study Start date:
July 01, 2023
Estimated Completion Date:
January 01, 2024

Connect with a study center

  • Fondazione Policlinico Universitario A. Gemelli - IRCCS

    Roma, 00168
    Italy

    Site Not Available

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