An Observational Study to Validate the Cumulative Life Course Impairment (CLCI) Instrument (DermCLCI-p) in Adult Participants With Moderate to Severe Chronic Plaque Psoriasis (PsO)

Last updated: April 30, 2025
Sponsor: AbbVie
Overall Status: Completed

Phase

N/A

Condition

Rosacea

Skin Wounds

Rash

Treatment

N/A

Clinical Study ID

NCT05959070
P23-435
  • Ages > 18
  • All Genders

Study Summary

The IMMagine study aims to validate the newly developed CLCI instrument (DermCLCI-p) in moderate to severe psoriasis (PsO) patients, who will be started on Risankizumb (RZB) treatment and will be enrolled into the validation study up to 28 weeks. The treatment decision for RZB must be made independent of this study enrollment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Confirmed diagnosis of moderate to severe chronic plaque-type psoriasis diagnosed bya dermatologist and presence of moderate to severe psoriasis symptoms according tophysician's clinical judgment at the time of recruitment.

  • Participants initiating RZB treatment for psoriasis as per local label. Physician'sdecision for treatment with risankizumab must have been reached prior to andindependently of recruitment in the study.

  • Participants able to understand and communicate with the investigator and complywith the requirements of the study.

  • Willingness and ability to comply with all study requirements.

Exclusion

Exclusion Criteria:

  • Current or recent (within the last 30 days) participation in an interventionalclinical trial.

Study Design

Total Participants: 154
Study Start date:
November 09, 2023
Estimated Completion Date:
March 21, 2025

Connect with a study center

  • Universite Libre de Bruxelles - Hopital Erasme /ID# 252456

    Anderlecht, Bruxelles-Capitale 1070
    Belgium

    Site Not Available

  • Université Libre de Bruxelles - Hôpital Erasme /ID# 252456

    Anderlecht, Bruxelles-Capitale 1070
    Belgium

    Active - Recruiting

  • Cliniques Universitaires de Bruxelles Hopital Erasme /ID# 252456

    Brussels, Bruxelles-Capitale 1070
    Belgium

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 253234

    Bruxelles, Bruxelles-Capitale 1200
    Belgium

    Site Not Available

  • Cliniques Universitaires UCL Saint-Luc /ID# 253234

    Woluwe-Saint-Lambert, Bruxelles-Capitale 1200
    Belgium

    Site Not Available

  • UCL Saint-Luc /ID# 253234

    Woluwe-Saint-Lambert, Bruxelles-Capitale 1200
    Belgium

    Active - Recruiting

  • UZ Gent /ID# 252458

    Gent, Oost-Vlaanderen 9000
    Belgium

    Site Not Available

  • Dermatologie Maldegem /ID# 252454

    Maldegem, Oost-Vlaanderen 9990
    Belgium

    Site Not Available

  • Universitair Ziekenhuis Leuven /ID# 252457

    Leuven, Vlaams-Brabant 3000
    Belgium

    Site Not Available

  • Wiseman Dermatology Research /ID# 255883

    Winnipeg, Manitoba R3M 3Z4
    Canada

    Site Not Available

  • Dermatrials Research /ID# 253879

    Hamilton, Ontario L8N 1Y2
    Canada

    Site Not Available

  • Lynde Institute for Dermatology /ID# 253876

    Markham, Ontario L3P 1X2
    Canada

    Site Not Available

  • Lynderm Research Inc. /ID# 253876

    Markham, Ontario L3P 1X3
    Canada

    Active - Recruiting

  • JRB Research /ID# 253877

    Ottawa, Ontario K1H 7X3
    Canada

    Site Not Available

  • SKiN Centre for Dermatology /ID# 255882

    Peterborough, Ontario K9J 5K2
    Canada

    Site Not Available

  • Dre Angelique Gagne-Henley M.D. inc. /ID# 262591

    Saint-Jerome, Quebec J7Z 7E2
    Canada

    Site Not Available

  • Hautarztpraxis Mortazawi /ID# 255872

    Remscheid, Nordrhein-Westfalen 42897
    Germany

    Site Not Available

  • Dermatologische Praxis Dr. med. Marvin Kuske /ID# 265688

    Dresden, 01109
    Germany

    Site Not Available

  • Universitaetsklinikum Hamburg-Eppendorf /ID# 254340

    Hamburg, 20246
    Germany

    Site Not Available

  • Gemeinschaftspraxis Dres. Anika Hünermund/Mario Pawlak /ID# 255874

    Heilbad Heiligenstadt, 37308
    Germany

    Site Not Available

  • Praxis Dres. Wiemers/Wiemers /ID# 255873

    Leipzig, 04317
    Germany

    Site Not Available

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