The BASA Study: Breath Analysis for Severe Asthma Patients

Last updated: July 13, 2023
Sponsor: Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Overall Status: Active - Recruiting

Phase

N/A

Condition

Asthma

Treatment

exhaled breath analysis

Clinical Study ID

NCT05946421
Università di Palermo
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study will evaluate the fluctuations of exhaled breath markers in patients with severe asthma on biologics. In the study, severe asthma patients will be followed up to 16 weeks monitoring lung function and inflammation through non-invasive technologies such as exhaled breath analysis (FeNO, GC-MS and EBC). A control group will be followed up to two weeks with the overall objective to indentify and evaluate the modifcations of markers of inflammation in patient under biologic treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Severe asthma diagnosis according to the latest recommendation
  • Eligible or in treatment with a biologic treatment for severe asthma
  • Able to follow istructions
  • Able and willing to sign the informed consent

Exclusion

Exclusion Criteria:

  • Not able to perform lung function measurements and the procedures of the study
  • Acute respiratory or non respiratory infection (<4 weeks)
  • Not willing to continue the study

Study Design

Total Participants: 100
Treatment Group(s): 1
Primary Treatment: exhaled breath analysis
Phase:
Study Start date:
July 04, 2023
Estimated Completion Date:
September 04, 2024

Connect with a study center

  • AOUP Policlinico Paolo Giaccone

    Palermo, 90100
    Italy

    Active - Recruiting

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