Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

Last updated: July 12, 2023
Sponsor: Shanghai Zhongshan Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cardiac Surgery

Treatment

passive leg raising

Dobutamine

Clinical Study ID

NCT05944146
Cracard
  • Ages 18-80
  • All Genders

Study Summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • adult cardiac surgery patients
  • with thermodilution technique monitoring
  • mechanical ventilation

Exclusion

Exclusion Criteria:

  • life threatening arrhythmia
  • severe valve regurgitation
  • left ventricular ejection fraction less than 30%
  • patients with mechanical circulatory support

Study Design

Total Participants: 200
Treatment Group(s): 2
Primary Treatment: passive leg raising
Phase:
Study Start date:
May 31, 2023
Estimated Completion Date:
December 31, 2026

Connect with a study center

  • Zhongshan hospital Fudan University

    Shanghai, Shanghai 200040
    China

    Active - Recruiting

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