mPATH for Low-income Older Adults

Last updated: April 9, 2025
Sponsor: Johns Hopkins University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Insomnia

Memory Problems

Memory Loss

Treatment

mPATH

Attention Control

Clinical Study ID

NCT05935241
IRB00396390
1R01AG080613-01A1
  • Ages > 65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • self-reported difficulty of sleep

  • lack of physical activity/exercise

  • low household income

  • capacity for moderate intensity exercise

Exclusion

Exclusion Criteria:

  • untreated sleep apnea

  • severe depression or anxiety

  • dementia

  • history of neurologic or psychiatric disorders, neurodevelopmental impairment,traumatic brain injury

  • current enrollment in another clinical trial

Study Design

Total Participants: 176
Treatment Group(s): 2
Primary Treatment: mPATH
Phase:
Study Start date:
May 30, 2024
Estimated Completion Date:
December 31, 2029

Study Description

Low-income older adults (LIOA) are a population at higher risk to develop Alzheimer's disease and related dementias (ADRD) and sleep disturbances. Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in LIOA. The growing wearable device and mobile Health (mHealth) provide an innovative approach to deliver individually tailored physical activity interventions at home with flexible schedules to overcome barriers to physical activity in LIOA. In addition, limited research has examined if physical activity interventions impact the individual's Amyloid/Tau/ Neurodegeneration (ATN) Alzheimer's disease biological state and whether physical activity may promote cognition through impacting sleep and AD pathology. This randomized controlled trial is designed to examine the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in LIOA. mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months.

Connect with a study center

  • The Johns Hopkins University, School of Nursing

    Baltimore, Maryland 21205
    United States

    Active - Recruiting

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