Establishment of a Tissue Registry for Hepatocellular Carcinoma Specimens

Last updated: June 28, 2023
Sponsor: Nikomed Medical Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carcinoma

Liver Disorders

Abdominal Cancer

Treatment

N/A

Clinical Study ID

NCT05935189
NMC-2301
  • All Genders

Study Summary

The goal of the study is to establish a cancer registry to facilitate research and assist in the identification of additional risk factors for hepatocellular carcinoma. The main objectives are:

  1. provide a mechanism to store the information about subjects with hepatocellular carcinoma

  2. use of tissue samples for translational/further research purposes

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with biopsy-confirmed diagnosis of HCC
  • Armenian descent
  • Having given their signed Informed consent

Exclusion

Exclusion Criteria:

  • Failure to obtain informed consent

Study Design

Total Participants: 500
Study Start date:
July 01, 2023
Estimated Completion Date:
July 01, 2028

Study Description

The Establishment of a Tissue Registry for Hepatocellular Carcinoma biopsy specimens for genetic and histologic research (TIR-HCC) is a project aimed at addressing the high incidence rates of primary liver cancer in Armenia. This initiative seeks to establish a cancer registry to support research efforts and identify additional risk factors associated with hepatocellular carcinoma (HCC).

The study will involve patients of Armenian descent who exhibit clinical, biochemical, and imaging evidence of hepatocellular carcinoma. Data collection will include tissue and blood samples, which will undergo histologic and genetic analyses. Additionally, relevant clinical history, laboratory results, imaging findings, and gut microbiota profiles will be collected.

To ensure a comprehensive dataset, samples will be collected from eight institutions in Armenia. The project aims to accumulate data from a total of 500 patients, providing a substantial pool for research and analysis.

By establishing the TIR-HCC registry, researchers hope to contribute to the understanding of hepatocellular carcinoma and potentially identify new risk factors associated with the disease. The collected data will aid in advancing knowledge of HCC and guide future strategies for prevention, early detection, and treatment.

Connect with a study center

  • Nikomed Medical Center

    Yerevan,
    Armenia

    Active - Recruiting

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