Design: This study will be conducted as a randomized controlled trial comparing effects
of ER to a WLC of participants with persistent pain when ER is provided by ER-trained
ASPMN nurses. The secondary aims of feasibility and acceptability will use qualitative
descriptive methods.
Participants: Participants (N=170) will be adults aged 18 and above years with self-
reported or clinically diagnosed persistent pain. Participants will be recruited at
clinical sites identified by ER-trained nurses and can be self or clinician referred.
Participants will complete an online eligibility form to screen for inclusion and
exclusion criteria. Inclusion criteria: pain >3 months more than half the time, English
fluency, ability to attend a one-time web-based class and complete web-based surveys, age
> 18 years. Exclusion criteria: Previous participation in ER class, cognitive impairment,
non-English speaking, or psychological factors that would preclude comprehension of
material or full participation in the study as determined by the investigators.
Procedures: Twenty ASPMN nurses will receive ER training facilitated by Stanford Pain
Relief Innovations Lab. ER- trained nurse providers will be ASPMN-member nurses of any
clinical background. ASPMN nurses will be invited to apply to become a trainer with the
following expectations: ability to fully participate in a live, online, 2-day ER
instructor training, able to fluently complete instructor training and deliver the ER
program in English, commitment to deliver 1-3 live, online, 2-hour ER programs for
patient participants, and willingness to complete post-program surveys after each session
they deliver reporting on number of participants and any barriers encountered.
Recruitment will occur through ASPMN-related mechanisms of communication, including its
website, national officers and directors, newsletter, research group, national
committees, chapter leadership and listserv.
After meeting eligibility criteria and completing informed consent, study participants
will be asked to complete a baseline survey of demographics and health variables (as
outlined in Table 1) and then randomized 1:1 to one of two unblinded study groups: ER and
WLC. Participants randomized to the ER group will complete a HIPAA compliant, password
protected Zoom ER class delivered by an ER-trained ASPMN nurse. A crossover intervention
class will be offered to those patient participants randomized to WLC once the ER group
has completed their class and follow up assessments, estimated at 2 months post
intervention.