TCM Daoyin in the Treatment of Patients With Anxiety State

Phase

N/A

Condition

Anxiety Disorders

Panic Disorders

Mood Disorders

Treatment

Health education

TCM Daoyin

Clinical Study ID

NCT05932095

ZY(2021-2023)- 0105-07

Ages 18-65
All Genders
Accepts Healthy Volunteers

Study Summary

In recent years, the number of people with symptoms of anxiety are on the rise. TCM Daoyin is a promising intervention for anxiety. This study is designed to allow researchers to better understand the changes in anxiety symptom, brain activity, and immune function during patients with anxiety states receiving TCM Daoyin intervention. Thus, the aims of the prospective randomized study are: (1) to examine the effects of TCM Daoyin training on reducing symptoms of anxiety, (2) to measure brain activity by using functional magnetic resonance imaging (fMRI), and (3) to assess Immune function.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Subject with a primary mental health complaint of anxiety.
Anxiety 14≤HAMA-14≤29, Depression 7≤HAMD-17<14.
Subject has no history of psychotropic medication or has been off medication formore than 6 months.
Right-handed, aged 18 to 65, male or female.
Subject has a clear mind and the ability to lead an independent life.
Subject agrees to participate in fMRI scan and provide signed informed consent.

Exclusion

Exclusion Criteria:

Subject with definite clinical diagnosis of anxiety disorder and depression disorderby ICD-10.
Subject with bipolar disorder, psychotic disorder (e.g., schizophrenia), organicmental disorder (e.g., Alzheimer's disease).
Subject with alcohol abuse, substance dependence and suicidal ideation in past-year,or currently taking psychiatric medication, or current serious suicidal attempt.
Subject with serious current unstable medical illness.
Subject has claustrophobia, or any contraindication unable or unwilling toparticipate in fMRI scan.
Subject is clinically unable to participate in TCM Daoyin training program.
Subject is pregnant or lactating women.

Study Design

Health education

June 13, 2023

March 20, 2025

Study Description

Anxiety is one of the most common mental health problems in the world. But there is a lack of sufficient no-drug intervention for relieving the anxious symptoms. The study focuses on mild and early anxiety disorder, which symptoms are not sufficiently severe, numerous, or persistent to justify a diagnosis of an anxiety disorder.

TCM Daoyin is a form of mind-body exercise with a profound philosophical foundation rooted in Chinese culture. Previous studies have provided some evidence of beneficial effects on TCM Daoyin for anxiety, such as Baduanjin and Liuzijue. However, the effects and neurophysiology mechanisms of TCM Daoyin on patients with anxiety state are yet to be further investigated.

This is a two-group prospective, randomized, assessor-blinded trial, planning to enroll 20 participants (10 for TCM Daoyin intervention group receiving health education plus a TCM Daoyin training program, and 10 for health education control group only receiving health education).

The aims of the prospective randomized study are: (1) to examine the effects of TCM Daoyin training on reducing symptoms of anxiety, (2) to measure brain activity by using functional magnetic resonance imaging (fMRI), and (3) to assess Immune function.

Connect with a study center

Shanghai Qigong Research Institute
Shanghai, Shanghai 021
China
Site Not Available

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