Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer

Last updated: June 6, 2023
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City
Overall Status: Completed

Phase

3

Condition

Acute And Chronic Dental Pain

Treatment

Calcium silicate-based sealers (CSS)

Epoxy resin-based sealers (ERS)

Clinical Study ID

NCT05904184
452/HD-DHYD
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Background: Sealers have been concerned with obturation. However, studies for assessing the effectiveness of endodontic treatment of sealer based on Calcium Silicate have been not much.

Objective: This study aimed to assess the effectiveness of endodontic treatment of sealer based on Calcium Silicate Methods: A prospective, single-blind, clinical trial was conducted from June 2020 to December 2020 with 42 irreversible pulpitis teeth by one clinician. The postoperative pain was assessed after root canal treatment using sealer based on Calcium Silicate and sealer based on Epoxy resin after 6 hours, 12 hours, 24 hours, 48 hours, 72 hours and 7 days and inconvenient symptoms were assessed after 7 days, 3 months and 6 months. t-test, Mann-Whitney and Wilcoxon analysis were applied.

Key words: obturation, sealer based on Calcium Silicate and sealer based on Epoxy resin

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • aged 18 years or older
  • teeth diagnosed with irreversible pulpitis by electrical and thermal tests (+)
  • had clinical symptoms like continuous or spontaneous pain, teeth exposed to suddentemperature changes, especially cold stimuli, causing sharp pain and persisting afterstimulus removal
  • these teeth must have healthy periodontal tissue and sufficient clinical teeth crownfor isolation with a rubber dam

Exclusion

Exclusion criteria: Patients with:

  • Pregnant
  • Have a systemic disease requiring antibiotics or have an allergic reaction
  • Have maxillofacial pathology, cellulitis, occlusal trauma, and temporomandibulardisorders, have endodontic periodontal lesions, periodontal abscesses
  • Have taken a previous pain reliever within 24 hours Tooth:
  • Roots internally or externally resorbed, cracked or broken
  • Have had failed endodontic treatment, or the root canal cannot be controlled forleakage
  • No opposing teeth

Study Design

Total Participants: 42
Treatment Group(s): 2
Primary Treatment: Calcium silicate-based sealers (CSS)
Phase: 3
Study Start date:
June 01, 2020
Estimated Completion Date:
December 31, 2021

Connect with a study center

  • University of Medicine and Pharmacy at Ho Chi Minh City

    Ho Chi Minh City, 72700
    Vietnam

    Site Not Available

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