Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation

Last updated: August 22, 2023
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Bone Density

Treatment

alveolar ridge preservation with bio-oss collagen

alveolar ridge preservation with sticky bone

Clinical Study ID

NCT05902689
2023-0369
  • Ages 18-70
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the control group underwent alveolar ridge preservation using Bio-Oss Collagen and the experimental group using Sticky Bone, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. The presence of one adjacent tooth at the extraction site
  2. Adequate oral hygiene (plaque index <20%;bleeding on probing <25% )
  3. Need for tooth extraction due to endodontic,periapical or periodontal disease.
  4. Presence of ≥ 2 mm of keratinized tissue
  5. the extraction sockets have no more than 50% of buccal alveolar bone loss(Integrity ofalveolar bone walls)

Exclusion

Exclusion Criteria:

  1. Pregnancy or lactation
  2. Smoking more than 10 cigarettes per day
  3. with no evidence of acute infection such as severe swelling, suppuration at theextraction site
  4. Uncontrolled periodontal disease
  5. Existence of bone metabolic disease
  6. history of malignancy, radiotherapy, or chemotherapy in the past 5 years
  7. Administration of bisphosphonates
  8. long-term use of NSAIDs
  9. Alcohol or drug abuse
  10. Infectious disease, such as hepatitis or human immunodeficiency virus (HIV) and/oracquired immunodeficiency syndrome (AIDS)
  11. Uncontrolled severe diabetes.( hemoglobin A1c >6.7%)

Study Design

Total Participants: 30
Treatment Group(s): 2
Primary Treatment: alveolar ridge preservation with bio-oss collagen
Phase:
Study Start date:
May 31, 2023
Estimated Completion Date:
June 01, 2024

Study Description

Within 6 months after tooth extraction, the remaining alveolar ridge undergoes varying degrees of absorption, resulting in a decrease in horizontal width and vertical height of the alveolar ridge. The three-dimensional size change of the alveolar socket may affect the implantation of later implants and cause aesthetic and functional problems. Alveolar ridge preservation can maintain the volume of the alveolar socket, prevent soft tissue from growing into undesirable positions, slow down the absorption of the alveolar ridge to some extent, promote new bone formation, and maintain the shape of the extraction socket. This is crucial for later implant treatment for missing teeth. In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the control group underwent alveolar ridge preservation using Bio-Oss Collagen and the experimental group using Sticky Bone, respectively, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation

Connect with a study center

  • 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China

    Hangzhou, Zhejiang
    China

    Active - Recruiting

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