A Post-Market Clinical Performance and Safety Evaluation of GamCath HighFlow Dolphin Protect Catheter

Inclusion Criteria:

• Patients ≥ 18 years of age at the time of catheter insertion.

• Patients diagnosed with AKI, ARF, and/or CKD (including end-stage renal disease [ESRD]).

• Patients who required vascular access to perform extracorporeal blood purificationusing GamCath HighFlow Dolphin Protect Catheter inserted by a physician in thesubclavian, jugular, or femoral veins.

Exclusion Criteria:

• Patients who required the GamCath HighFlow Dolphin Protect Catheter for anyindication other than extracorporeal blood purification.

• Patients who had a local infection at the vascular access site prior to catheterinsertion.

• Patients who required surgical intervention (e.g., cutdown procedure) for GamCathHighFlow Dolphin Protect Catheter placement.

• Patients who had a prior catheter in place at the same vascular access site (i.e.,R/L jugular vein, R/L femoral vein, R/L subclavian vein) within the last 7 days.

• Patients who do not have complete patient records to support the primary endpointanalyses.