Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust

Last updated: September 1, 2023
Sponsor: Rennes University Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Limb Spasticity

Cataplexy

Treatment

isokinetic strength training of knee extensor and flexor muscles

Clinical Study ID

NCT05887440
35RC20_9899_ISOWALK
  • Ages 18-75
  • All Genders

Study Summary

The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Hemiparetic patient (hemorragic or ischemic stroke)
  • Subacute stage (< 6 Months) ou chronic stage of stroke (> 6 months) (6 patients ineach group)
  • Age between 18 and 75 years
  • Able to walk 10 meters independently without any assistive devices
  • Knee extension thrust during stance phase of gait cycle (rapid posterior movement ofthe knee toward extension)
  • Scheduled rehabilitation program with isokinetic strength training
  • affiliation to a social security
  • Patients who received and signed informed consent

Exclusion

Exclusion Criteria:

  • Major comprehension deficit that not allow to give informed consent and participate toisokinetic strength training (assessed with comprehension subscore of Langaguescreening Test)
  • non stable (unstable cardiovascular condition)
  • musculoskeletal disorders with knee pain that not allowed isokinetic strength training
  • Botulinum toxin injection less than 3 months or repeated injection in lower limb,
  • Proprioception trouble assessed with proprioception section of the Fugl-MeyerAssessment [FMA-P] 0/2
  • spasticity of triceps surae ≥2 (Modified Ashworth scale)
  • ankle dorsiflexion angle less than 90°
  • pregnant women or breastfeeding
  • persons with safety measure

Study Design

Total Participants: 12
Treatment Group(s): 1
Primary Treatment: isokinetic strength training of knee extensor and flexor muscles
Phase:
Study Start date:
August 21, 2023
Estimated Completion Date:
December 01, 2026

Study Description

The study will be interventional single case experimental design (SCED) with multiple baseline design. SCED are experimental designs aiming at testing the effect of an intervention using a small number of patients using repeated measurements, sequential and randomized introduction of an intervention and method-specific data analysis, including visual analysis and specific statistics.

During baseline, patients will have a rehabilitation program in day hospital (4 days per week) with physiotherapy and physical activity and if necessary occupational and speech therapy. Isokinetic strength training will be added to this conventionnal rehabilitation program and will begin after 3, 4 or 5 weeks of baseline according to randomization

12 patients will be included in this study (6 patients in subacute stage and 6 in chronic stage ).

Connect with a study center

  • CHU de Rennes

    Rennes, 35033
    France

    Active - Recruiting

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